A geranylated biphenyl derivative from Garcinia mangostana

被引:19
作者
Dharmaratne, HRW [1 ]
Piyasena, KGNP [1 ]
Tennakoon, SB [1 ]
机构
[1] Inst Fundamental Studies, Nat Prod Programme, Kandy 20000, Sri Lanka
关键词
Garcinia mangostana; root bark; stem bark; latex; alpha-mangostin; beta-mangostin; gamma-mangostin; 3-hydroxy-4-geranyl-5-methoxybiphenyl;
D O I
10.1080/14786410410001710582
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Extracts of root bark, stem bark and the latex collected from the green fruits of Garcinia mangostana gave alpha-mangostin, beta-mangostin, gamma-mangostin, garcinone-E, methoxy-beta-mangostin and a new geranylated biphenyl derivative 3-hydroxy-4-geranyl-5-methoxybiphenyl. The latex of G. mangostana consists of more than 75% of xanthones which have strong antibacterial (anti-MRSA and -VRE), anti-inflammatory, antifungal and a number of other biological activities. Hence the presence of the above highly bioactive compounds in large quantities should be the causative factor for G. mangostana's medicinal value in indigenous medicine.
引用
收藏
页码:239 / 243
页数:5
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