Transmission of Middle East Respiratory Syndrome Coronavirus Infections in Healthcare Settings, Abu Dhabi

被引：102

作者：

Hunter, Jennifer C. ^{[1
]}

Duc Nguyen ^{[1
]}

Aden, Bashir ^{[2
]}

Al Bandar, Zyad ^{[2
]}

Al Dhaheri, Wafa ^{[2
]}

Abu Elkheir, Kheir ^{[2
]}

Khudair, Ahmed ^{[2
]}

Al Mulla, Mariam ^{[2
]}

El Saleh, Feda ^{[2
]}

Imambaccus, Hala ^{[3
]}

Al Kaabi, Nawal ^{[3
]}

Sheikh, Farrukh Amin ^{[3
]}

Sasse, Jurgen ^{[3
]}

Turner, Andrew ^{[3
]}

Wareth, Laila Abdel ^{[3
]}

Weber, Stefan ^{[3
]}

Al Ameri, Asma ^{[4
]}

Abu Amer, Wesal ^{[4
]}

Alami, Negar N. ^{[1
]}

Bunga, Sudhir ^{[1
]}

Haynes, Lia M. ^{[1
]}

Hall, Aron J. ^{[1
]}

Kallen, Alexander J. ^{[1
]}

Kuhar, David ^{[1
]}

Huong Pham ^{[1
]}

Pringle, Kimberly ^{[1
]}

Tong, Suxiang ^{[1
]}

Whitaker, Brett L. ^{[1
]}

Gerber, Susan I. ^{[1
]}

Al Hosani, Farida Ismail ^{[2
]}

机构：

[1] Ctr Dis Control & Prevent, Atlanta, GA USA

[2] Hlth Author Abu Dhabi, Abu Dhabi, U Arab Emirates

[3] Abu Dhabi Hlth Serv Co, Abu Dhabi, U Arab Emirates

[4] Sheikh Khalifa Med City, Mol Diagnost Lab, Abu Dhabi, U Arab Emirates

来源：

EMERGING INFECTIOUS DISEASES | 2016年 / 22卷 / 04期

关键词：

SAUDI-ARABIA; FAMILY CLUSTER; OUTBREAK; RIYADH; JEDDAH;

D O I：

10.3201/eid2204.151615

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Middle East respiratory syndrome coronavirus (MERS-CoV) infections sharply increased in the Arabian Peninsula during spring 2014. In Abu Dhabi, United Arab Emirates, these infections occurred primarily among healthcare workers and patients. To identify and describe epidemiologic and clinical characteristics of persons with healthcare-associated infection, we reviewed laboratory-confirmed MERS-CoV cases reported to the Health Authority of Abu Dhabi during January 1, 2013 May 9, 2014. Of 65 case-patients identified with MERS-CoV infection, 27 (42%) had healthcare-associated cases. Epidemiologic and genetic sequencing findings suggest that 3 healthcare clusters of MERS-CoV infection occurred, including 1 that resulted in 20 infected persons in 1 hospital. MERS-CoV in healthcare settings spread predominantly before MERS-CoV infection was diagnosed, underscoring the importance of increasing awareness and infection control measures at first points of entry to healthcare facilities.

引用

页码：647 / 656

页数：10

共 27 条

[1] Hospital-Associated Outbreak of Middle East Respiratory Syndrome Coronavirus: A Serologic, Epidemiologic, and Clinical Description
Al-Abdallat, Mohammad Mousa
Payne, Daniel C.
Alqasrawi, Sultan
Rha, Brian
Tohme, Rania A.
Abedi, Glen R.
Al Nsour, Mohannad
Iblan, Ibrahim
Jarour, Najwa
Farag, Noha H.
Haddadin, Aktham
Al-Sanouri, Tarek
Tamin, Azaibi
Harcourt, Jennifer L.
Kuhar, David T.
Swerdlow, David L.
Erdman, Dean D.
Pallansch, Mark A.
Haynes, Lia M.
Gerber, Susan I.
[J]. CLINICAL INFECTIOUS DISEASES, 2014, 59 (09) : 1225 - 1233
[2] Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study
Assiri, Abdullah
Al-Tawfiq, Jaffar A.
Al-Rabeeah, Abdullah A.
Al-Rabiah, Fahad A.
Al-Hajjar, Sami
Al-Barrak, Ali
Flemban, Hesham
Al-Nassir, Wafa N.
Balkhy, Hanan H.
Al-Hakeem, Rafat F.
Makhdoom, Hatem Q.
Zumla, Alimuddin I.
Memish, Ziad A.
[J]. LANCET INFECTIOUS DISEASES, 2013, 13 (09) : 752 - 761
[3] Hospital Outbreak of Middle East Respiratory Syndrome Coronavirus
Assiri, Abdullah
McGeer, Allison
Perl, Trish M.
Price, Connie S.
Al Rabeeah, Abdullah A.
Cummings, Derek A. T.
Alabdullatif, Zaki N.
Assad, Maher
Almulhim, Abdulmohsen
Makhdoom, Hatem
Madani, Hossam
Alhakeem, Rafat
Al-Tawfiq, Jaffar A.
Cotten, Matthew
Watson, Simon J.
Kellam, Paul
Zumla, Alimuddin I.
Memish, Ziad A.
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2013, 369 (05) : 407 - 416
[4] Centers for Disease Control and Prevention, 2015, INT PAT INV PUI GUID
[5] MERS Coronaviruses in Dromedary Camels, Egypt
Chu, Daniel K. W.
Poon, Leo L. M.
Gomaa, Mokhtar M.
Shehata, Mahmoud M.
Perera, Ranawaka A. P. M.
Abu Zeid, Dina
El Rifay, Amira S.
Siu, Lewis Y.
Guan, Yi
Webby, Richard J.
Ali, Mohamed A.
Peiris, Malik
Kayali, Ghazi
[J]. EMERGING INFECTIOUS DISEASES, 2014, 20 (06) : 1049 - 1053
[6] Corman VM, 2012, EUROSURVEILLANCE, V17, P2
[7] Corman VM, 2012, EUROSURVEILLANCE, V17, P3
[8] Transmission and evolution of the Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive genomic study
Cotten, Matthew
Watson, Simon J.
Kellam, Paul
Al-Rabeeah, Abdullah A.
Makhdoom, Hatem Q.
Assiri, Abdullah
Al-Tawfiq, Jaffar A.
Alhakeem, Rafat F.
Madani, Hossam
AlRabiah, Fahad A.
Al Hajjar, Sami
Al-Nassir, Wafa N.
Albarrak, Ali
Flemban, Hesham
Balkhy, Hanan H.
Alsubaie, Sarah
Palser, Anne L.
Gall, Astrid
Bashford-Rogers, Rachael
Rambaut, Andrew
Zumla, Alimuddin I.
Memish, Ziad A.
[J]. LANCET, 2013, 382 (9909) : 1993 - 2002
[9] Full-Genome Deep Sequencing and Phylogenetic Analysis of Novel Human Betacoronavirus
Cotten, Matthew
Lam, Tommy T.
Watson, Simon J.
Palser, Anne L.
Petrova, Velislava
Grant, Paul
Pybus, Oliver G.
Rambaut, Andrew
Guan, Yi
Pillay, Deenan
Kellam, Paul
Nastouli, Eleni
[J]. EMERGING INFECTIOUS DISEASES, 2013, 19 (05) : 736 - 742
[10] Preliminary epidemiological assessment of MERS-CoV outbreak in South Korea, May to June 2015
Cowling, B. J.
Park, M.
Fang, V. J.
Wu, P.
Leung, G. M.
Wu, J. T.
[J]. EUROSURVEILLANCE, 2015, 20 (25) : 7 - 13

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