Palladium-catalyzed direct functionalization of imidazolinone: Synthesis of dibromophakellstatin

被引：78

作者：

Lu, Jianming ^{[1
]}

Tan, Xianghui ^{[1
]}

Chen, Chuo ^{[1
]}

机构：

[1] Univ Texas, SW Med Ctr, Dept Biochem, Dallas, TX 75390 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 25期

关键词：

D O I：

10.1021/ja072844p

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The direct C-H functionalization of imidazolinone is achieved with Pd(OAc)(2)/NaOAc in DMSO. Dibromophakellstatin can be synthesized in five steps with 40% overall yield using this new C-H activation method.

引用

页码：7768 / +

页数：3

共 53 条

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