First synthesis of 2′,3′-epimino-carbocydic nucleosides

被引：19

作者：

Ishikura, M ^{[1
]}

Murakami, A ^{[1
]}

Katagiri, N ^{[1
]}

机构：

[1] Hlth Sci Univ Hokkaido, Fac Pharmaceut Sci, Ishikari, Hokkaido 0610293, Japan

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2003年 / 1卷 / 03期

关键词：

D O I：

10.1039/b210963h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The preparation of 2',3'-epimino-carbocyclic analogues of adenosine is reported. The reaction of p-tosyl azide with N-substituted 2-azabicyclo[2.2.1]hept-5-en-3-one (ABH) (1a) provided aziridine-fused ABH (2), which was converted to 2',3'-epimino-carbocyclic nucleosides (11).

引用

页码：452 / 453

页数：2

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