Host factors exploited by retroviruses

被引：206

作者：

Goff, Stephen P.

机构：

[1] Columbia Univ Coll Phys & Surg, Dept Biochem & Mol Biophys, New York, NY 10032 USA

[2] Columbia Univ Coll Phys & Surg, Dept Microbiol, Howard Hughes Med Inst, New York, NY 10032 USA

来源：

NATURE REVIEWS MICROBIOLOGY | 2007年 / 5卷 / 04期

关键词：

D O I：

10.1038/nrmicro1541

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Retroviruses make a long and complex journey from outside the cell to the nucleus in the early stages of infection, and then an equally long journey back out again in the late stages of infection. Ongoing efforts are identifying an enormous array of cellular proteins that are used by the viruses in the course of their travels. These host factors are potential new targets for therapeutic intervention.

引用

收藏

页码：253 / 263

页数：11

相关论文

共 177 条

[111] Mapping of tetraspanin-enriched microdomains that can function as gateways for HIV-1 [J].

Nydegger, Sascha ;

Khurana, Sandhya ;

Krementsov, Dimitry N. ;

Foti, Michelangelo ;

Thali, Markus .

JOURNAL OF CELL BIOLOGY, 2006, 173 (05) :795-807

[112] Innate antiviral response targets HIV-1 release by the induction of ubiquitin-like protein ISG15 [J].

Okumura, A ;

Lu, GS ;

Pitha-Rowe, I ;

Pitha, PM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (05) :1440-1445

[113] Relationship between human immunodeficiency virus type 1 Gag multimerization and membrane binding [J].

Ono, A ;

Demirov, D ;

Freed, EO .

JOURNAL OF VIROLOGY, 2000, 74 (11) :5142-5150

[114] Cell-type-dependent targeting of human immunodeficiency virus type 1 assembly to the plasma membrane and the multivesicular body [J].

Ono, A ;

Freed, EO .

JOURNAL OF VIROLOGY, 2004, 78 (03) :1552-1563

[115] Reverse transcriptase of Moloney murine leukemia virus binds to eukarvotic release factor 1 to modulate suppression of translational termination [J].

Orlova, M ;

Yueh, A ;

Leung, J ;

Goff, SP .

CELL, 2003, 115 (03) :319-331

[116] Ubiquitin is covalently attached to the p6Gag proteins of human immunodeficiency virus type 1 and simian immunodeficiency virus and to the p12Gag protein of Moloney murine leukemia virus [J].

Ott, DE ;

Coren, LV ;

Copeland, TD ;

Kane, BP ;

Johnson, DG ;

Sowder, RC ;

Yoshinaka, Y ;

Oroszlan, S ;

Arthur, LO ;

Henderson, LE .

JOURNAL OF VIROLOGY, 1998, 72 (04) :2962-2968

[117] Cytoskeletal proteins inside human immunodeficiency virus type 1 virions [J].

Ott, DE ;

Coren, LV ;

Kane, BP ;

Busch, LK ;

Johnson, DG ;

Sowder, RC ;

Chertova, EN ;

Arthur, LO ;

Henderson, LE .

JOURNAL OF VIROLOGY, 1996, 70 (11) :7734-7743

[118] Receptors and entry cofactors for retroviruses include single and multiple transmembrane-spanning proteins as well as newly described glycophosphatidylinositol-anchored and secreted proteins [J].

Overbaugh, J ;

Miller, AD ;

Eiden, MV .

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 2001, 65 (03) :371-+

[119] Opposing effects of human immunodeficiency virus type 1 matrix mutations support a myristyl switch model of Gag membrane targeting [J].

Paillart, JC ;

Göttlinger, HG .

JOURNAL OF VIROLOGY, 1999, 73 (04) :2604-2612

[120] Infectious HIV-1 assembles in late endosomes in primary macrophages [J].

Pelchen-Matthews, A ;

Kramer, B ;

Marsh, M .

JOURNAL OF CELL BIOLOGY, 2003, 162 (03) :443-455

← 7 8 9 10 11 12 13 14 15 16 →