Nickel(II) chloride catalyzed one-pot synthesis of α-aminonitriles

被引：95

作者：

De, SK

机构：

[1] Dept. Med. Chem. Molec. Pharmacol., School of Pharmacy, Purdue Cancer Ctr., Purdue Univ., W.

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2005年 / 225卷 / 02期

关键词：

aldehydes; amines; trimethylsilyl cyanide; alpha-aminonitriles; nickel(II) chloride;

D O I：

10.1016/j.molcata.2004.09.005

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A simple and efficient method has been developed for the synthesis of alpha-aminonitrilesby simply mixing aldehydes, amines, and trimethylsilyl cyanides in the presence of a catalytic amount of NiCl2 at room temperature. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：169 / 171

页数：3

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