The NCBI BioSystems database

被引:591
作者
Geer, Lewis Y. [1 ]
Marchler-Bauer, Aron [1 ]
Geer, Renata C. [1 ]
Han, Lianyi [1 ]
He, Jane [1 ]
He, Siqian [1 ]
Liu, Chunlei [1 ]
Shi, Wenyao [1 ]
Bryant, Stephen H. [1 ]
机构
[1] NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bethesda, MD 20894 USA
基金
美国国家卫生研究院;
关键词
PATHWAY; INFORMATION; RESOURCES; BIOLOGY;
D O I
10.1093/nar/gkp858
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The NCBI BioSystems database, found at http://www.ncbi.nlm.nih.gov/biosystems/, centralizes and cross-links existing biological systems databases, increasing their utility and target audience by integrating their pathways and systems into NCBI resources. This integration allows users of NCBI's Entrez databases to quickly categorize proteins, genes and small molecules by metabolic pathway, disease state or other BioSystem type, without requiring time-consuming inference of biological relationships from the literature or multiple experimental datasets.
引用
收藏
页码:D492 / D496
页数:5
相关论文
共 13 条
  • [1] Pathguide: a Pathway Resource List
    Bader, Gary D.
    Cary, Michael P.
    Sander, Chris
    [J]. NUCLEIC ACIDS RESEARCH, 2006, 34 : D504 - D506
  • [2] The Universal Protein Resource (UniProt) 2009
    Bairoch, Amos
    Consortium, UniProt
    Bougueleret, Lydie
    Altairac, Severine
    Amendolia, Valeria
    Auchincloss, Andrea
    Argoud-Puy, Ghislaine
    Axelsen, Kristian
    Baratin, Delphine
    Blatter, Marie-Claude
    Boeckmann, Brigitte
    Bolleman, Jerven
    Bollondi, Laurent
    Boutet, Emmanuel
    Quintaje, Silvia Braconi
    Breuza, Lionel
    Bridge, Alan
    deCastro, Edouard
    Ciapina, Luciane
    Coral, Danielle
    Coudert, Elisabeth
    Cusin, Isabelle
    Delbard, Gwennaelle
    Dornevil, Dolnide
    Roggli, Paula Duek
    Duvaud, Severine
    Estreicher, Anne
    Famiglietti, Livia
    Feuermann, Marc
    Gehant, Sebastian
    Farriol-Mathis, Nathalie
    Ferro, Serenella
    Gasteiger, Elisabeth
    Gateau, Alain
    Gerritsen, Vivienne
    Gos, Arnaud
    Gruaz-Gumowski, Nadine
    Hinz, Ursula
    Hulo, Chantal
    Hulo, Nicolas
    James, Janet
    Jimenez, Silvia
    Jungo, Florence
    Junker, Vivien
    Kappler, Thomas
    Keller, Guillaume
    Lachaize, Corinne
    Lane-Guermonprez, Lydie
    Langendijk-Genevaux, Petra
    Lara, Vicente
    [J]. NUCLEIC ACIDS RESEARCH, 2009, 37 : D169 - D174
  • [3] The systems biology markup language (SBML):: a medium for representation and exchange of biochemical network models
    Hucka, M
    Finney, A
    Sauro, HM
    Bolouri, H
    Doyle, JC
    Kitano, H
    Arkin, AP
    Bornstein, BJ
    Bray, D
    Cornish-Bowden, A
    Cuellar, AA
    Dronov, S
    Gilles, ED
    Ginkel, M
    Gor, V
    Goryanin, II
    Hedley, WJ
    Hodgman, TC
    Hofmeyr, JH
    Hunter, PJ
    Juty, NS
    Kasberger, JL
    Kremling, A
    Kummer, U
    Le Novère, N
    Loew, LM
    Lucio, D
    Mendes, P
    Minch, E
    Mjolsness, ED
    Nakayama, Y
    Nelson, MR
    Nielsen, PF
    Sakurada, T
    Schaff, JC
    Shapiro, BE
    Shimizu, TS
    Spence, HD
    Stelling, J
    Takahashi, K
    Tomita, M
    Wagner, J
    Wang, J
    [J]. BIOINFORMATICS, 2003, 19 (04) : 524 - 531
  • [4] KEGG for linking genomes to life and the environment
    Kanehisa, Minoru
    Araki, Michihiro
    Goto, Susumu
    Hattori, Masahiro
    Hirakawa, Mika
    Itoh, Masumi
    Katayama, Toshiaki
    Kawashima, Shuichi
    Okuda, Shujiro
    Tokimatsu, Toshiaki
    Yamanishi, Yoshihiro
    [J]. NUCLEIC ACIDS RESEARCH, 2008, 36 : D480 - D484
  • [5] Expansion of the BioCyc collection of pathway/genome databases to 160 genomes
    Karp, PD
    Ouzounis, CA
    Moore-Kochlacs, C
    Goldovsky, L
    Kaipa, P
    Ahrén, D
    Tsoka, S
    Darzentas, N
    Kunin, V
    López-Bigas, N
    [J]. NUCLEIC ACIDS RESEARCH, 2005, 33 (19) : 6083 - 6089
  • [6] EcoCyc: A comprehensive view of Escherichia coli biology
    Keseler, Ingrid M.
    Bonavides-Martinez, Cesar
    Collado-Vides, Julio
    Gama-Castro, Socorro
    Gunsalus, Robert P.
    Johnson, D. Aaron
    Krummenacker, Markus
    Nolan, Laura M.
    Paley, Suzanne
    Paulsen, Ian T.
    Peralta-Gil, Martin
    Santos-Zavaleta, Alberto
    Glennon Shearer, Alexander
    Karp, Peter D.
    [J]. NUCLEIC ACIDS RESEARCH, 2009, 37 : D464 - D470
  • [7] Klein T. E., 2001, Pharmacogenomics Journal, V1, P167
  • [8] PAX of mind for pathway researchers
    Luciano, JS
    [J]. DRUG DISCOVERY TODAY, 2005, 10 (13) : 937 - 942
  • [9] Reactome knowledgebase of human biological pathways and processes
    Matthews, Lisa
    Gopinath, Gopal
    Gillespie, Marc
    Caudy, Michael
    Croft, David
    de Bono, Bernard
    Garapati, Phani
    Hemish, Jill
    Hermjakob, Henning
    Jassal, Bijay
    Kanapin, Alex
    Lewis, Suzanna
    Mahajan, Shahana
    May, Bruce
    Schmidt, Esther
    Vastrik, Imre
    Wu, Guanming
    Birney, Ewan
    Stein, Lincoln
    D'Eustachio, Peter
    [J]. NUCLEIC ACIDS RESEARCH, 2009, 37 : D619 - D622
  • [10] GenMAPP 2: new features and resources for pathway analysis
    Salomonis, Nathan
    Hanspers, Kristina
    Zambon, Alexander C.
    Vranizan, Karen
    Lawlor, Steven C.
    Dahlquist, Kam D.
    Doniger, Scott W.
    Stuart, Josh
    Conklin, Bruce R.
    Pico, Alexander R.
    [J]. BMC BIOINFORMATICS, 2007, 8 (1)