Lipase catalysis in ionic liquids and supercritical carbon dioxide at 150°C

被引：129

作者：

Lozano, P

De Diego, T

Carrié, D

Vaultier, M

Iborra, JL

机构：

[1] Univ Murcia, Fac Quim, Dept Bioquim & Biol Mol & Inmunol B, E-30100 Murcia, Spain

[2] Univ Rennes, Inst Chim, CNRS, UMR 6510, F-35042 Rennes, France

来源：

BIOTECHNOLOGY PROGRESS | 2003年 / 19卷 / 02期

关键词：

D O I：

10.1021/bp025759o

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Free and immobilized Candida antarctica lipase B dispersed in ionic liquids (1-ethyl-3-methylimidazolium bistriflimide and 1-buthyl-3-methylimidazolium bistriflimide) were used as catalyst for the continuous kinetic resolution of rac-1-phenylethanol in supercritical carbon dioxide at 120 and 150degreesC and 10 MPa. Excellent activity, stability and enantioselectivity levels were recorded in continuous operation.

引用

页码：380 / 382

页数：3

共 14 条

[1] High-pressure phase behavior of ionic liquid/CO2 systems
Blanchard, LA
Gu, ZY
Brennecke, JF
[J]. JOURNAL OF PHYSICAL CHEMISTRY B, 2001, 105 (12) : 2437 - 2444
[2] Ionic liquid (molten salt) phase organometallic catalysis
Dupont, J
de Souza, RF
Suarez, PAZ
[J]. CHEMICAL REVIEWS, 2002, 102 (10) : 3667 - 3691
[3] REDUCING ENZYME CONFORMATIONAL FLEXIBILITY BY MULTIPOINT COVALENT IMMOBILIZATION
FERNANDEZLAFUENTE, R
WOOD, ANP
COWAN, DA
[J]. BIOTECHNOLOGY TECHNIQUES, 1995, 9 (01) : 1 - 6
[4] New horizons for ionic liquids -: Green 'designer solvents' find additional effective uses, now for enzyme catalysis and in classic organic synthesis
Freemantle, M
[J]. CHEMICAL & ENGINEERING NEWS, 2001, 79 (01) : 21 - 25
[5] BIOCATALYTIC SYNTHESIS OF ACRYLATES IN ORGANIC-SOLVENTS AND SUPERCRITICAL FLUIDS .3. DOES CARBON-DIOXIDE COVALENTLY MODIFY ENZYMES
KAMAT, S
CRITCHLEY, G
BECKMAN, EJ
RUSSELL, AJ
[J]. BIOTECHNOLOGY AND BIOENGINEERING, 1995, 46 (06) : 610 - 620
[6] Improving enzymes by using them in organic solvents
Klibanov, AM
[J]. NATURE, 2001, 409 (6817) : 241 - 246
[7] Stability of immobilized alpha-chymotrypsin in supercritical carbon dioxide
Lozano, P
Avellaneda, A
Pascual, R
Iborra, JL
[J]. BIOTECHNOLOGY LETTERS, 1996, 18 (11) : 1345 - 1350
[8] Continuous green biocatalytic processes using ionic liquids and supercritical carbon dioxide
Lozano, P
de Diego, T
Carrié, D
Vaultier, M
Iborra, JL
[J]. CHEMICAL COMMUNICATIONS, 2002, (07) : 692 - 693
[9] Stabilization of α-chymotrypsin by ionic liquids in transesterification reactions
Lozano, P
de Diego, T
Guegan, JP
Vaultier, M
Iborra, JL
[J]. BIOTECHNOLOGY AND BIOENGINEERING, 2001, 75 (05) : 563 - 569
[10] Over-stabilization of Candida antarctica lipase B by ionic liquids in ester synthesis
Lozano, P
De Diego, T
Carrié, D
Vaultier, M
Iborra, JL
[J]. BIOTECHNOLOGY LETTERS, 2001, 23 (18) : 1529 - 1533

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