Absence of xenotropic murine leukemia virus-related virus in blood cells of men at risk for and infected with HIV

被引：17

作者：

Kunstman, Kevin J.

BhattacharyaB, Tanmoy ^{[2
]}

Flaherty, John

Phair, John P.

Wolinsky, Steven M. ^{[1
]}

机构：

[1] Northwestern Univ, Feinberg Sch Med, Dept Med, Div Infect Dis, Chicago, IL 60611 USA

[2] Santa Fe Inst, Santa Fe, NM 87501 USA

来源：

AIDS | 2010年 / 24卷 / 11期

关键词：

CHRONIC-FATIGUE-SYNDROME; PROSTATE-CANCER; XMRV; RETROVIRUS;

D O I：

10.1097/QAD.0b013e32833b76fb

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Xenotropic murine leukemia virus-related virus has been detected in blood cells of patients with chronic fatigue syndrome and in 3.7% of healthy controls from the same geographic region. We evaluated 996 men who were participants in the Multicenter AIDS Cohort Study for xenotropic murine leukemia virus-related virus sequences in blood cells by means of a real-time quantitative PCR assay. Xenotropic murine leukemia virus-related virus was detected in none of the men on the basis of the absence of xenotropic murine leukemia virus-related virus DNA, suggesting that infection may be population-specific.

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收藏

页码：1784 / 1785

页数：2

相关论文

共 8 条

[1]

Bhattacharya T, 2009, NAT MED, V15, P1112, DOI 10.1038/nm1009-1112

[2] A New Virus for Old Diseases? [J].

Coffin, John M. ;

Stoye, Jonathan P. .

SCIENCE, 2009, 326 (5952) :530-531

[3] Lack of evidence for xenotropic murine leukemia virus-related virus(XMRV) in German prostate cancer patients [J].

Hohn, Oliver ;

Krause, Hans ;

Barbarotto, Pia ;

Niederstadt, Lars ;

Beimforde, Nadine ;

Denner, Joachim ;

Miller, Kurt ;

Kurth, Reinhard ;

Bannert, Norbert .

RETROVIROLOGY, 2009, 6 :92

[4] Fibrils of Prostatic Acid Phosphatase Fragments Boost Infections with XMRV (Xenotropic Murine Leukemia Virus-Related Virus), a Human Retrovirus Associated with Prostate Cancer [J].

Hong, Seunghee ;

Klein, Eric A. ;

Das Gupta, Jaydip ;

Hanke, Kirsten ;

Weight, Christopher J. ;

Nguyen, Carvell ;

Gaughan, Christina ;

Kim, Kyeong-Ae ;

Bannert, Norbert ;

Kirchhoff, Frank ;

Munch, Jan ;

Silverman, Robert H. .

JOURNAL OF VIROLOGY, 2009, 83 (14) :6995-7003

[5] RETRACTED: Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome (Retracted article. See vol. 334, pg. 1636, 2011) [J].

Lombardi, Vincent C. ;

Ruscetti, Francis W. ;

Das Gupta, Jaydip ;

Pfost, Max A. ;

Hagen, Kathryn S. ;

Peterson, Daniel L. ;

Ruscetti, Sandra K. ;

Bagni, Rachel K. ;

Petrow-Sadowski, Cari ;

Gold, Bert ;

Dean, Michael ;

Silverman, Robert H. ;

Mikovits, Judy A. .

SCIENCE, 2009, 326 (5952) :585-589

[6] Xenotropic Murine Leukemia Virus-Related Virus Establishes an Efficient Spreading Infection and Exhibits Enhanced Transcriptional Activity in Prostate Carcinoma Cells [J].

Rodriguez, Jason J. ;

Goff, Stephen P. .

JOURNAL OF VIROLOGY, 2010, 84 (05) :2556-2562

[7] RETRACTED: XMRV is present in malignant prostatic epithelium and is associated with prostate cancer, especially high-grade tumors (Retracted article. See vol. 111, pg. 12270, 2014) [J].

Schlaberg, Robert ;

Choe, Daniel J. ;

Brown, Kristy R. ;

Thaker, Harshwardhan M. ;

Singh, Ila R. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (38) :16351-16356

[8] Prevalence of xenotropic murine leukaemia virus-related virus in patients with chronic fatigue syndrome in the Netherlands: retrospective analysis of samples from an established cohort [J].

van Kuppeveld, Frank J. M. ;

de Jong, Arjan S. ;

Lanke, Kjerstin H. ;

Verhaegh, Gerald W. ;

Melchers, Willem J. G. ;

Swanink, Caroline M. A. ;

Bleijenberg, Gijs ;

Netea, Mihai G. ;

Galama, Jochem M. D. ;

van der Meer, Jos W. M. .

BMJ-BRITISH MEDICAL JOURNAL, 2010, 340 :520