Template-directed reversible photocircularization of DNA via 5-vinyldeoxycytidine

被引：27

作者：

Fujimoto, K ^{[1
]}

Matsuda, S ^{[1
]}

Ogawa, N ^{[1
]}

Hayashi, M ^{[1
]}

Saito, I ^{[1
]}

机构：

[1] Kyoto Univ, Dept Synthet Chem & Biol Chem, Kyoto 6068501, Japan

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 33期

关键词：

D O I：

10.1016/S0040-4039(00)01025-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient and reversible template-directed photoligation of oligodeoxynucleotides (ODNs) using 5-vinyldeoxycytidine (C-V) was described. When ODN containing C-V at the 5' end was photoirradiated with ODN containing thymine at the 3' end in the presence of a template ODN, an efficient photoligation was observed. Reversible photopadlocking of a circular DNA by the photocircularization using C-V was demonstrated. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：6451 / 6454

页数：4

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