A selective optical sensor based on [9]mercuracarborand-3, a new type of ionophore with a chloride complexing cavity

被引:52
作者
Badr, IHA [1 ]
Johnson, RD [1 ]
Diaz, M [1 ]
Hawthorne, MF [1 ]
Bachas, LG [1 ]
机构
[1] Univ Kentucky, Dept Chem, Lexington, KY 40506 USA
关键词
D O I
10.1021/ac000508k
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A highly selective optical sensor for chloride, based on the multidentate Lewis acid ionophore [9]mercuracarborand-3, is described herein. This sensor is constructed by embedding the mercuracarborand ionophore, a suitable pH-sensitive lipophilic dye, and lipophilic cationic sites in a plasticized polymeric membrane. The multiple complementary interactions offered by the preorganized complexing cavity of [9]mercuracarborand-3 is shown to control the anion selectivity pattern of the optical film. The film exhibits a significantly enhanced selectivity for chloride over a variety of lipophilic anions such as perchlorate, nitrate, salicylate, and thiocyanate. Furthermore, the optical selectivity coefficients obtained for chloride over other biologically relevant anions are shown to meet the selectivity requirements for the determination of chloride in physiological fluids, unlike previously reported chloride optical sensors. In addition, the optical film responds to chloride reversibly over a wide dynamic range (16 mu M-136 mM) with fast response and recovery times.
引用
收藏
页码:4249 / 4254
页数:6
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