Synthesis of silica-coated semiconductor and magnetic quantum dots and their use in the imaging of live cells

被引:451
作者
Selvan, S. Tamil [1 ]
Patra, Pranab K. [1 ]
Ang, Chung Yen [1 ]
Ying, Jackie Y. [1 ]
机构
[1] Inst Bioengn & Nanotechnol, Singapore 138669, Singapore
关键词
bioconjugation; luminescence; magnetic properties; quantum dots;
D O I
10.1002/anie.200604245
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Figure Presented) Bifunctional nanocomposites comprising semiconductor and magnetic nanoparticles are of interest in biological applications for biolabeling, bioimaging, and cell separation. To this end, a nanocomposite system that consists of Fe2O3 magnetic nanoparticles and CdSe quantum dots and which exhibits superparamagnetism and tunable emission properties was prepared and used to label different live cell membranes (see picture). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:2448 / 2452
页数:5
相关论文
共 55 条
[21]   Synthesis and characterization of Co/CdSe core/shell nanocomposites: Bifunctional magnetic-optical nanocrystals [J].
Kim, H ;
Achermann, M ;
Balet, LP ;
Hollingsworth, JA ;
Klimov, VI .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (02) :544-546
[22]   Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping [J].
Kim, S ;
Lim, YT ;
Soltesz, EG ;
De Grand, AM ;
Lee, J ;
Nakayama, A ;
Parker, JA ;
Mihaljevic, T ;
Laurence, RG ;
Dor, DM ;
Cohn, LH ;
Bawendi, MG ;
Frangioni, JV .
NATURE BIOTECHNOLOGY, 2004, 22 (01) :93-97
[23]   Cytotoxicity of colloidal CdSe and CdSe/ZnS nanoparticles [J].
Kirchner, C ;
Liedl, T ;
Kudera, S ;
Pellegrino, T ;
Javier, AM ;
Gaub, HE ;
Stölzle, S ;
Fertig, N ;
Parak, WJ .
NANO LETTERS, 2005, 5 (02) :331-338
[24]   A single-electron transistor made from a cadmium selenide nanocrystal [J].
Klein, DL ;
Roth, R ;
Lim, AKL ;
Alivisatos, AP ;
McEuen, PL .
NATURE, 1997, 389 (6652) :699-701
[25]   Optical gain and stimulated emission in nanocrystal quantum dots [J].
Klimov, VI ;
Mikhailovsky, AA ;
Xu, S ;
Malko, A ;
Hollingsworth, JA ;
Leatherdale, CA ;
Eisler, HJ ;
Bawendi, MG .
SCIENCE, 2000, 290 (5490) :314-317
[26]   γ-Fe2O3/II-VI sulfide nanocrystal heterojunctions [J].
Kwon, KW ;
Shim, M .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (29) :10269-10275
[27]   Synthesis of nanosized gold-silica core-shell particles [J].
Liz-Marzan, LM ;
Giersig, M ;
Mulvaney, P .
LANGMUIR, 1996, 12 (18) :4329-4335
[28]   Generation of superparamagnetic liposomes revealed as highly efficient MRI contrast agents for in vivo imaging [J].
Martina, MS ;
Fortin, JP ;
Ménager, C ;
Clément, O ;
Barratt, G ;
Grabielle-Madelmont, C ;
Gazeau, F ;
Cabuil, V ;
Lesieur, S .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (30) :10676-10685
[29]   Quantum dot bioconjugates for imaging, labelling and sensing [J].
Medintz, IL ;
Uyeda, HT ;
Goldman, ER ;
Mattoussi, H .
NATURE MATERIALS, 2005, 4 (06) :435-446
[30]   Quantum dots for live cells, in vivo imaging, and diagnostics [J].
Michalet, X ;
Pinaud, FF ;
Bentolila, LA ;
Tsay, JM ;
Doose, S ;
Li, JJ ;
Sundaresan, G ;
Wu, AM ;
Gambhir, SS ;
Weiss, S .
SCIENCE, 2005, 307 (5709) :538-544