Mobile genetic elements colonizing the genomes of metazoan parasites

被引：36

作者：

Brindley, PJ ^{[1
]}

Laha, T

McManus, DP

Loukas, A

机构：

[1] Tulane Univ, Ctr Hlth Sci, Dept Trop Med, New Orleans, LA 70112 USA

[2] Khon Kaen Univ, Fac Med, Dept Parasitol, Khon Kaen 40002, Thailand

[3] Queensland Inst Med Res, Australian Ctr Int & Trop Hlth & Nutr, Brisbane, Qld 4029, Australia

[4] George Washington Univ, Dept Microbiol & Trop Med, Washington, DC 20037 USA

来源：

TRENDS IN PARASITOLOGY | 2003年 / 19卷 / 02期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/S1471-4922(02)00061-2

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

A substantial fraction of the genome of most eukaryotes, including those of metazoan parasites, is predicted to comprise repetitive sequences. Mobile genetic elements (MGEs) will make up much of these repetitive sequences, particularly the interspersed sequences. This article reviews information on MGEs that have colonized the genomes of metazoan parasites (i.e. parasites of parasites). Helminth and mosquito genomes, in particular, are compared with those of better-understood model organisms. MGEs from the genomes of metazoan parasites can be expected to have practical uses in transgenesis and epidemiological studies.

引用

页码：79 / 87

页数：9

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