Considering the cancer consequences of altered DNA polymerase function

被引：44

作者：

Kunkel, TA

机构：

[1] NIEHS, Mol Genet Lab, NIH, DHHS, Res Triangle Pk, NC 27709 USA

[2] NIEHS, Struct Biol Lab, NIH, DHHS, Res Triangle Pk, NC 27709 USA

来源：

CANCER CELL | 2003年 / 3卷 / 02期

关键词：

D O I：

10.1016/S1535-6108(03)00027-8

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Our appreciation of the DNA transactions that replicate and maintain a stable human genome is changing rapidly due to recent discoveries indicating that eukaryotic cells contain many more DNA polymerases than previously thought. This review describes emerging information on the properties and functions of human DNA polymerases, with emphasis on connections between DNA polymerase functions and cancer.

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收藏

页码：105 / 110

页数：6

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