Mycobacterium avium subsp paratuberculosis strains isolated from Crohn's disease patients and animal species exhibit similar polymorphic locus patterns

被引:71
作者
Ghadiali, AH
Strother, M
Naser, SA
Manning, EJB
Sreevatsan, S
机构
[1] Ohio State Univ, FAHRP, OARDC, Wooster, OH 44691 USA
[2] Ohio State Univ, Dept Vet Prevent Med, Wooster, OH 44691 USA
[3] Univ Cent Florida, Dept Mol Biol & Microbiol, Orlando, FL USA
[4] Univ Wisconsin, Sch Vet Med, Dept Pathobiol Sci, Madison, WI USA
关键词
D O I
10.1128/JCM.42.11.5345-5348.2004
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Analysis of short sequence repeats of Mycobacterium avium subsp. paratuberculosis isolated from Crohn's disease patients identified two alleles, both of which clustered with strains derived from animals with Johne's disease. Identification of a limited number of genotypes among human strains implies the existence of human disease-associated genotypes and strain sharing with animals.
引用
收藏
页码:5345 / 5348
页数:4
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