Basal transcription factors

被引：48

作者：

Reese, JC ^{[1
]}

机构：

[1] Penn State Univ, Dept Biochem & Mol Biol, Althouse Lab 203, University Pk, PA 16802 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2003年 / 13卷 / 02期

关键词：

D O I：

10.1016/S0959-437X(03)00013-3

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The functions of the basal transcription factors involved in RNA polymerase 11 dependent transcription have been the focus of many years of biochemical analysis. Recent advances have shed some light on the structure of these factors, how conformational changes and intramolecular interactions regulate activity, and have revealed an expanded role for TFIIH in nuclear transcription.

引用

页码：114 / 118

页数：5

共 45 条

[11] Activator-mediated disruption of sequence-specific DNA contacts by the general transcription factor TFIIB [J].

Evans, R ;

Fairley, JA ;

Roberts, SGE .

GENES & DEVELOPMENT, 2001, 15 (22) :2945-2949

[12] Core promoter-dependent TFIIB conformation and a role for TFIIB conformation in transcription start site selection [J].

Fairley, JA ;

Evans, R ;

Hawkes, NA ;

Roberts, SGE .

MOLECULAR AND CELLULAR BIOLOGY, 2002, 22 (19) :6697-6705

[13] Promoter-specific shifts in transcription initiation conferred by yeast TFIIB mutations are determined by the sequence in the immediate vicinity of the start sites [J].

Faitar, SL ;

Brodie, SA ;

Ponticelli, AS .

MOLECULAR AND CELLULAR BIOLOGY, 2001, 21 (14) :4427-4440

[14] The histone fold is a key structural motif of transcription factor TFIID [J].

Gangloff, YG ;

Romier, C ;

Thuault, S ;

Werten, S ;

Davidson, I .

TRENDS IN BIOCHEMICAL SCIENCES, 2001, 26 (04) :250-257

[15] TBP-associated factors (TAFIIs):: multiple, selective transcriptional mediators in common complexes [J].

Green, MR .

TRENDS IN BIOCHEMICAL SCIENCES, 2000, 25 (02) :59-63

[16] MULTIPLE FUNCTIONAL DOMAINS OF HUMAN TRANSCRIPTION FACTOR-IIB - DISTINCT INTERACTIONS WITH 2 GENERAL TRANSCRIPTION FACTORS AND RNA POLYMERASE-II [J].

HA, I ;

ROBERTS, S ;

MALDONADO, E ;

SUN, XQ ;

KIM, LU ;

GREEN, M ;

REINBERG, D .

GENES & DEVELOPMENT, 1993, 7 (06) :1021-1032

[17] Molecular genetics of the RNA polymerase II general transcriptional machinery [J].

Hampsey, M .

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 1998, 62 (02) :465-+

[18] The conformation of the transcription factor TFIIB modulates the response to transcriptional activators in vivo [J].

Hawkes, NA ;

Evans, R ;

Roberts, SGE .

CURRENT BIOLOGY, 2000, 10 (05) :273-276

[19] The role of human TFIIB in transcription start site selection in vitro and in vivo [J].

Hawkes, NA ;

Roberts, SGE .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (20) :14337-14343

[20] Human general transcription factor TFIIB: Conformational variability and interaction with VP16 activation domain [J].

Hayashi, F ;

Ishima, R ;

Liu, DJ ;

Tong, KI ;

Kim, S ;

Reinberg, D ;

Bagby, S ;

Ikura, M .

BIOCHEMISTRY, 1998, 37 (22) :7941-7951

← 1 2 3 4 5 →