Mutagenesis of a novel gene in the prcA-prtP protease locus affects expression of Treponema denticola membrane complexes

被引：30

作者：

Bian, XL

Wang, HT

Ning, Y

Lee, SY

Fenno, JC ^{[1
]}

机构：

[1] Univ Michigan, Sch Dent, Dept Biol & Mat Sci, Ann Arbor, MI 48109 USA

[2] Kangnung Natl Univ, Coll Dent, Dept Oral Microbiol, Kangnung, South Korea

来源：

INFECTION AND IMMUNITY | 2005年 / 73卷 / 02期

关键词：

D O I：

10.1128/IAI.73.2.1252-1255.2005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A novel gene was identified in the Treponema denticola prcA-prtP protease operon. Strains with mutations in either the prcA-prtP or the msp region showed altered expression of a product(s) of the other locus. Together, these results provide information on the assembly of outer membrane complexes involved in T. denticola interaction with host cells and tissue.

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页码：1252 / 1255

页数：4

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