Real-time multi-functional optical coherence tomography

被引:133
作者
Park, BH [1 ]
Pierce, MC [1 ]
Cense, B [1 ]
de Boer, JF [1 ]
机构
[1] Massachusetts Gen Hosp, Wellman Labs Photomed, Boston, MA 02114 USA
来源
OPTICS EXPRESS | 2003年 / 11卷 / 07期
关键词
D O I
10.1364/OE.11.000782
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We demonstrate real-time acquisition, processing, and display of tissue structure, birefringence, and blood flow in a multi-functional optical coherence tomography (MF-OCT) system. This is accomplished by efficient data processing of the phase-resolved inteference patterns without dedicated hardware or extensive modification to the high-speed fiber-based OCT system. The system acquires images of 2048 depth scans per second, covering an area of 5 mm in width x 1.2 mm in depth with real-time display updating images in a rolling manner 32 times each second. We present a video of the system display as images from the proximal nail fold of a human volunteer are taken. (C) 2003 Optical Society of America.
引用
收藏
页码:782 / 793
页数:12
相关论文
共 27 条
[1]   Noninvasive imaging of in vivo blood flow velocity using optical Doppler tomography [J].
Chen, ZP ;
Milner, TE ;
Srinivas, S ;
Wang, XJ ;
Malekafzali, A ;
vanGemert, MJC ;
Nelson, JS .
OPTICS LETTERS, 1997, 22 (14) :1119-1121
[2]   Imaging thermally damaged tissue by polarization sensitive optical coherence tomography [J].
de Boer, JF ;
Srinivas, SM ;
Malekafzali, A ;
Chen, ZP ;
Nelson, JS .
OPTICS EXPRESS, 1998, 3 (06) :212-218
[3]   Determination of the depth-resolved Stokes parameters of light backscattered from turbid media by use of polarization-sensitive optical coherence tomography [J].
de Boer, JF ;
Milner, TE ;
Nelson, JS .
OPTICS LETTERS, 1999, 24 (05) :300-302
[4]   Stable carrier generation and phase-resolved digital data processing in optical coherence tomography [J].
de Boer, JF ;
Saxer, CE ;
Nelson, JS .
APPLIED OPTICS, 2001, 40 (31) :5787-5790
[5]   Two-dimensional birefringence imaging in biological tissue by polarization-sensitive optical coherence tomography [J].
deBoer, JF ;
Milner, TE ;
vanGemert, MJC ;
Nelson, JS .
OPTICS LETTERS, 1997, 22 (12) :934-936
[6]   In vivo ultrahigh-resolution optical coherence tomography [J].
Drexler, W ;
Morgner, U ;
Kärtner, FX ;
Pitris, C ;
Boppart, SA ;
Li, XD ;
Ippen, EP ;
Fujimoto, JG .
OPTICS LETTERS, 1999, 24 (17) :1221-1223
[7]   Birefringence characterization of biological tissue by use of optical coherence tomography [J].
Everett, MJ ;
Schoenenberger, K ;
Colston, BW ;
Da Silva, LB .
OPTICS LETTERS, 1998, 23 (03) :228-230
[8]   Imaging caries lesions and lesion progression with polarization sensitive optical coherence tomography [J].
Fried, D ;
Xie, J ;
Shafi, S ;
Featherstone, JDB ;
Breunig, TM ;
Le, C .
JOURNAL OF BIOMEDICAL OPTICS, 2002, 7 (04) :618-627
[9]   OPTICAL COHERENCE TOMOGRAPHY [J].
HUANG, D ;
SWANSON, EA ;
LIN, CP ;
SCHUMAN, JS ;
STINSON, WG ;
CHANG, W ;
HEE, MR ;
FLOTTE, T ;
GREGORY, K ;
PULIAFITO, CA ;
FUJIMOTO, JG .
SCIENCE, 1991, 254 (5035) :1178-1181
[10]   In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomograghy [J].
Izatt, JA ;
Kulkami, MD ;
Yazdanfar, S ;
Barton, JK ;
Welch, AJ .
OPTICS LETTERS, 1997, 22 (18) :1439-1441