A highly selective long-wavelength fluorescent probe for the detection of human carboxylesterase 2 and its biomedical applications

被引：83

作者：

Feng, Lei ^{[1
,2
]}

Liu, Zhao-Ming ^{[2
]}

Xu, Liang ^{[3
]}

Lv, Xia ^{[2
]}

Ning, Jing ^{[2
]}

Hou, Jie ^{[4
]}

Ge, Guang-Bo ^{[1
,2
]}

Cui, Jing-Nan ^{[1
]}

Yang, Ling ^{[2
]}

机构：

[1] Dalian Univ Technol, State Key Lab Fine Chem, Dalian, Peoples R China

[2] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian, Peoples R China

[3] Dalian Univ Technol, Sch Chem, Dalian, Peoples R China

[4] Dalian Med Univ, Dalian 116044, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 93期

关键词：

LIVING CELLS; HUMAN LIVER; MAMMALIAN CARBOXYLESTERASES; CATALYTIC-PROPERTIES; IRINOTECAN; ACTIVATION; CPT-11; FLUOROPHORE; METABOLISM; PHARMACOKINETICS;

D O I：

10.1039/c4cc06642a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A highly selective long-wavelength fluorescent probe TCFB has been developed for the detection of hCE2. The probe can be used for real-time monitoring of hCE2 activity in complex biological systems.

引用

页码：14519 / 14522

页数：4

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