A novel DEAD-box RNA helicase exhibits high sequence conservation from yeast to humans

被引：10

作者：

Eisen, A ^{[1
]}

Sattah, M ^{[1
]}

Gazitt, T ^{[1
]}

Neal, K ^{[1
]}

Szauter, P ^{[1
]}

Lucchesi, J ^{[1
]}

机构：

[1] Emory Univ, Dept Biol, Atlanta, GA 30322 USA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1998年 / 1397卷 / 02期

关键词：

helicase; translation initiation; gene evolution; (Drosophila);

D O I：

10.1016/S0167-4781(97)00213-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have identified a novel Drosophila protein, DBF80, that exhibits significant similarity to mouse mDEAD5, yeast TIF1/2, and mammalian eIF-4A. DBP80 is a member of a subclass of DEAD-box proteins that contains a distinct domain. PX(I/R>ILLKR(E/D)EETLEGIKQ(F/Y)(F/Y), in addition to the seven canonical helicase domains. (C) 1998 Elsevier Science B.V.

引用

收藏

页码：131 / 136

页数：6

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