Meddling with methylation

被引：13

作者：

Hsieh, CL ^{[1
]}

Jones, PA

机构：

[1] Univ So Calif, Kenneth Norris Jr Comprehens Canc Ctr, Dept Biochem & Mol Biol, Los Angeles, CA 90089 USA

[2] Univ So Calif, Kenneth Norris Jr Comprehens Canc Ctr, Dept Urol, Los Angeles, CA 90089 USA

来源：

NATURE CELL BIOLOGY | 2003年 / 5卷 / 06期

关键词：

D O I：

10.1038/ncb0603-502

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Covalent modification of DNA by methylation is crucial for maintaining the stability and structure of chromatin. Reports of the effects that altered methylation has for cancer development stress the importance of balanced genomic methylation.

引用

页码：502 / 504

页数：3

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