Visualizing the laboratory mouse: capturing phenotype information

被引:14
作者
Strivens, M
Eppig, JT
机构
[1] Jackson Lab, Bar Harbor, ME 04609 USA
[2] Informat Grp, Mammalian Genet Unit, Didcot OX11 0RD, Oxon, England
[3] UK Mouse Genome Ctr, Didcot OX11 0RD, Oxon, England
关键词
database; informatics; mouse; mutagenesis; nomenclature; phenotype; vocabulary;
D O I
10.1007/s10709-004-1435-7
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
A concerted effort to develop myriad new phenotypic alleles through mutagenesis programs presents new challenges for the biomedical community and for the informatics infrastructure needed to support this work. To handle and co-ordinate large programs of treatment, breeding, and sequential or longitudinal testing for a variety of obvious and subtle traits requires sophisticated data management software. Further, trait analyses, heritability testing, and animal availability and status must be captured and disseminated to the wider community. The Mouse Genome Database (MGD) will serve as the central integration point for the various mutagenesis programs, registering new alleles, providing accession identifiers, and capturing phenotypic descriptions. In addition, MGD will provide public access to unified searches over all alleles with links to the centres of origin for detailed testing data.
引用
收藏
页码:89 / 97
页数:9
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