Theory of Midinfrared Absorption Microspectroscopy: I. Homogeneous Samples

被引:104
作者
Davis, Brynmor J. [1 ,2 ]
Carney, P. Scott [2 ,3 ]
Bhargava, Rohit [1 ,2 ]
机构
[1] Univ Illinois, Dept Bioengn, Urbana, IL 61801 USA
[2] Univ Illinois, Beckman Inst Adv Sci & Technol, Urbana, IL 61801 USA
[3] Univ Illinois, Dept Elect & Comp Engn, Urbana, IL 61801 USA
关键词
CHEMICALLY AMPLIFIED RESIST; X-RAY-LITHOGRAPHY; ELECTROMAGNETIC DIFFRACTION; IR SPECTROPHOTOMETRY; TRANSMISSION MEASUREMENTS; INFRARED INTENSITIES; DISPERSION ANALYSIS; OPTICAL-CONSTANTS; MICROSCOPY; SPECTROSCOPY;
D O I
10.1021/ac902067p
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Midinfrared (IR) microspectroscopy is widely employed for spatially localized spectral analyses. A comprehensive theoretical model for the technique, however, has not been previously proposed. In this paper, rigorous theory is presented for IR absorption microspectroscopy by using Maxwell's equations to model beam propagation. Focusing effects, material dispersion, and the geometry of the sample are accounted to predict spectral response for homogeneous samples. Predictions are validated experimentally using Fourier transform IR (FT-IR) microspectroscopic examination of a photoresist. The results emphasize that meaningful interpretation of IR microspectroscopic data must involve an understanding of the coupled optical effects associated with the sample, substrate properties, and microscopy configuration. Simulations provide guidance for developing experimental methods and future instrument design by quantifying distortions in the recorded data. Distortions are especially severe for transflection mode and for samples mounted on certain substrates. Last, the model generalizes to rigorously consider the effects of focusing. While spectral analyses range from examining gross spectral features to assessing subtle features using advanced chemometrics, the limitations imposed by these effects in the data acquisition on the information available are less clear. The distorting effects are shown to be larger than noise levels seen in modern spectrometers. Hence, the model provides a framework to quantify spectral distortions that may limit the accuracy of information or present confounding effects in microspectroscopy.
引用
收藏
页码:3474 / 3486
页数:13
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