Efficient stereoselective synthesis of the epoxyacid fragment of the azinomycins

被引：11

作者：

Coleman, RS ^{[1
]}

Sarko, CR ^{[1
]}

Gittinger, JP ^{[1
]}

机构：

[1] UNIV S CAROLINA,DEPT CHEM & BIOCHEM,COLUMBIA,SC 29208

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 34期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(97)01322-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three concise enantioselective synthetic routes to the C17-C21 epoxyacid segment of the azinomycins are presented and were based on a Sharpless asymmetric epoxidation/kinetic resolution of racemic allylic alcohol (+/-)-3 that occurred with reversal of the expected sense of enantioselection. (C) 1997 Elsevier Science Ltd.

引用

页码：5917 / 5920

页数：4

共 34 条

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