Chemoenzymatic synthesis of enantiomerically pure alkene 1,2-diols and glycosides thereof

被引：46

作者：

Ziegler, T ^{[1
]}

Bien, F ^{[1
]}

Jurisch, C ^{[1
]}

机构：

[1] Univ Cologne, Inst Organ Chem, D-50939 Cologne, Germany

来源：

TETRAHEDRON-ASYMMETRY | 1998年 / 9卷 / 05期

关键词：

D O I：

10.1016/S0957-4166(98)00051-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The kinetic resolution of racemic 2-O-acylated 3-butene-1,2-diol and 1-O-acylated 3-butene-1,2-diol derivatives by enzymatic saponification and enzymatic esterification, respectively, is investigated with several lipases and esterases. The resulting partially blocked enantiomers are glycosylated with glycosyl halides and trichloroacetimidates, respectively. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：765 / 780

页数：16

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