ENANTIOSELECTIVE REDUCTION OF BETA,GAMMA-UNSATURATED ALPHA-KETO ACIDS USING BACILLUS-STEAROTHERMOPHILUS LACTATE-DEHYDROGENASE - A NEW ROUTE TO FUNCTIONALIZED ALLYLIC ALCOHOLS

被引：26

作者：

CASY, G ^{[1
]}

LEE, TV ^{[1
]}

LOVELL, H ^{[1
]}

机构：

[1] UNIV BRISTOL, CTR MOLEC RECOGNIT, BRISTOL BS8 1TS, AVON, ENGLAND

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 06期

关键词：

D O I：

10.1016/S0040-4039(00)77723-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The enantioselective reduction of alpha-keto acids, catalysed by lactate dehydrogenase, has been extended to beta,chi-unsaturated substrates, providing functionalised allylic alcohols in high optical purity.

引用

页码：817 / 820

页数：4

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