FROM ANALYSIS TO SYNTHESIS - NEW LIGAND-BINDING SITES ON THE LACTATE-DEHYDROGENASE FRAMEWORK .2.

被引：84

作者：

CLARKE, AR ^{[1
]}

ATKINSON, T ^{[1
]}

HOLBROOK, JJ ^{[1
]}

机构：

[1] CTR APPL MICROBIOL & RES,DIV BIOTECHNOL,SALISBURY SP4 0JG,WILTS,ENGLAND

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1989年 / 14卷 / 04期

关键词：

D O I：

10.1016/0968-0004(89)90147-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：145 / 148

页数：4

共 15 条

[1] FROM ANALYSIS TO SYNTHESIS - NEW LIGAND-BINDING SITES ON THE LACTATE-DEHYDROGENASE FRAMEWORK .1.
CLARKE, AR
ATKINSON, T
HOLBROOK, JJ
[J]. TRENDS IN BIOCHEMICAL SCIENCES, 1989, 14 (03) : 101 - 105
[2] RATIONAL CONSTRUCTION OF A 2-HYDROXYACID DEHYDROGENASE WITH NEW SUBSTRATE-SPECIFICITY
CLARKE, AR
SMITH, CJ
HART, KW
WILKS, HM
CHIA, WN
LEE, TV
BIRKTOFT, JJ
BANASZAK, LJ
BARSTOW, DA
ATKINSON, T
HOLBROOK, JJ
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1987, 148 (01) : 15 - 23
[3] CHANGES IN THE STATE OF SUBUNIT ASSOCIATION OF LACTATE-DEHYDROGENASE FROM BACILLUS-STEAROTHERMOPHILUS
CLARKE, AR
WALDMAN, ADB
MUNRO, I
HOLBROOK, JJ
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1985, 828 (03) : 375 - 379
[4] A SINGLE AMINO-ACID SUBSTITUTION DEREGULATES A BACTERIAL LACTATE-DEHYDROGENASE AND STABILIZES ITS TETRAMERIC STRUCTURE
CLARKE, AR
WIGLEY, DB
BARSTOW, DA
CHIA, WN
ATKINSON, T
HOLBROOK, JJ
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1987, 913 (01) : 72 - 80
[5] THE ASSEMBLY MECHANISM OF THE LACTATE-DEHYDROGENASE TETRAMER FROM BACILLUS-STEAROTHERMOPHILUS - THE EQUILIBRIUM RELATIONSHIPS BETWEEN QUATERNARY STRUCTURE AND THE BINDING OF FRUCTOSE-1,6-BISPHOSPHATE, NADH AND OXAMATE
CLARKE, AR
ATKINSON, T
CAMPBELL, JW
HOLBROOK, JJ
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1985, 829 (03) : 387 - 396
[6] THE MOLECULAR PATHWAY BY WHICH FRUCTOSE-1,6-BISPHOSPHATE INDUCES THE ASSEMBLY OF A BACTERIAL LACTATE-DEHYDROGENASE
CLARKE, AR
EVINGTON, JRN
DUNN, CR
ATKINSON, T
HOLBROOK, JJ
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1986, 870 (01) : 112 - 126
[7] PROBING STERIC AND HYDROPHOBIC EFFECTS ON ENZYME-SUBSTRATE INTERACTIONS BY PROTEIN ENGINEERING
ESTELL, DA
GRAYCAR, TP
MILLER, JV
POWERS, DB
BURNIER, JP
NG, PG
WELLS, JA
[J]. SCIENCE, 1986, 233 (4764) : 659 - 663
[8] HYDROGEN-BONDING AND BIOLOGICAL SPECIFICITY ANALYZED BY PROTEIN ENGINEERING
FERSHT, AR
SHI, JP
KNILLJONES, J
LOWE, DM
WILKINSON, AJ
BLOW, DM
BRICK, P
CARTER, P
WAYE, MMY
WINTER, G
[J]. NATURE, 1985, 314 (6008) : 235 - 238
[9] SITE-DIRECTED MUTAGENESIS SHOWS THAT TYROSINE 248 OF CARBOXYPEPTIDASE-A DOES NOT PLAY A CRUCIAL ROLE IN CATALYSIS
GARDELL, SJ
CRAIK, CS
HILVERT, D
URDEA, MS
RUTTER, WJ
[J]. NATURE, 1985, 317 (6037) : 551 - 555
[10] A STRONG CARBOXYLATE-ARGININE INTERACTION IS IMPORTANT IN SUBSTRATE ORIENTATION AND RECOGNITION IN LACTATE-DEHYDROGENASE
HART, KW
CLARKE, AR
WIGLEY, DB
WALDMAN, ADB
CHIA, WN
BARSTOW, DA
ATKINSON, T
JONES, JB
HOLBROOK, JJ
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1987, 914 (03) : 294 - 298

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