Hooking Up with Oct4

被引：13

作者：

Lemischka, Ihor R. ^{[1
]}

机构：

[1] Mt Sinai Sch Med, Black Family Stem Cell Inst, New York, NY 10029 USA

来源：

CELL STEM CELL | 2010年 / 6卷 / 04期

关键词：

EMBRYONIC STEM-CELLS; PLURIPOTENCY;

D O I：

10.1016/j.stem.2010.03.011

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

The transcription factor Oct4 plays a central role in controlling the undifferentiated state of embryonic and induced pluripotent stem cells. Two complementary papers in this issue of Cell Stem Cell describe the extended network of proteins that interact with Oct4. Together, these studies broaden our understanding of the control of pluripotency.

引用

页码：291 / 292

页数：2

共 9 条

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Chambers, Ian ;

Tomlinson, Simon R. .

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[2] Epigenetic reprogramming and induced pluripotency [J].

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Plath, Kathrin .

DEVELOPMENT, 2009, 136 (04) :509-523

[3] Systems-level dynamic analyses of fate change in murine embryonic stem cells [J].

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Markowetz, Florian ;

Unwin, Richard D. ;

Leek, Jeffrey T. ;

Airoldi, Edoardo M. ;

MacArthur, Ben D. ;

Lachmann, Alexander ;

Rozov, Roye ;

Ma'ayan, Avi ;

Boyer, Laurie A. ;

Troyanskaya, Olga G. ;

Whetton, Anthony D. ;

Lemischka, Ihor R. .

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Klewe-Nebenius, D ;

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Schöler, H ;

Smith, A .

CELL, 1998, 95 (03) :379-391

[5] An Expanded Oct4 Interaction Network: Implications for Stem Cell Biology, Development, and Disease [J].

Pardo, Mercedes ;

Lang, Benjamin ;

Yu, Lu ;

Prosser, Haydn ;

Bradley, Allan ;

Babu, M. Madan ;

Choudhary, Jyoti .

CELL STEM CELL, 2010, 6 (04) :382-395

[6] Smarcc1/Baf155 Couples Self-Renewal Gene Repression with Changes in Chromatin Structure in Mouse Embryonic Stem Cells [J].

Schaniel, Christoph ;

Ang, Yen-Sin ;

Ratnakumar, Kajan ;

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James, Taneisha ;

Bernstein, Emily ;

Lemischka, Ihor R. ;

Paddison, Patrick J. .

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Yamanaka, Shinya .

CELL, 2006, 126 (04) :663-676

[8] An Oct4-Centered Protein Interaction Network in Embryonic Stem Cells [J].

van den Berg, Debbie L. C. ;

Snoek, Tim ;

Mullin, Nick P. ;

Yates, Adam ;

Bezstarosti, Karel ;

Demmers, Jeroen ;

Chambers, Ian ;

Poot, Raymond A. .

CELL STEM CELL, 2010, 6 (04) :369-381

[9] A protein interaction network for pluripotency of embryonic stem cells [J].

Wang, Jianlong ;

Rao, Sridhar ;

Chu, Jianlin ;

Shen, Xiaohua ;

Levasseur, Dana N. ;

Theunissen, Thorold W. ;

Orkin, Stuart H. .

NATURE, 2006, 444 (7117) :364-368

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