Powering an inorganic nanodevice with a biomolecular motor

被引:477
作者
Soong, RK
Bachand, GD
Neves, HP
Olkhovets, AG
Craighead, HG
Montemagno, CD [1 ]
机构
[1] Cornell Univ, Nanobiotechnol Ctr, Ithaca, NY 14853 USA
[2] Cornell Univ, Dept Agr & Biol Engn, Ithaca, NY 14853 USA
[3] Cornell Univ, Sch Appl & Engn Phys, Ithaca, NY 14853 USA
关键词
D O I
10.1126/science.290.5496.1555
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Biomolecular motors such as F-1-adenosine triphosphate synthase (F-1-ATPase) and myosin are similar in size, and they generate forces compatible with currently producible nanoengineered structures. We have engineered individual biomolecular motors and nanoscale inorganic systems, and we describe their integration in a hybrid nanomechanical device powered by a biomolecular motor. The device consisted of three components: an engineered substrate, an F-1-ATPase biomolecular motor; and fabricated nanopropellers. Rotation of the nanopropeller was initiated with 2 mM adenosine triphosphate and inhibited by sodium azide.
引用
收藏
页码:1555 / 1558
页数:4
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