Asymmetric synthesis of water-soluble, nonhydrolyzable phosphonate analogue of phosphatidylinositol 4,5-bisphosphate

被引：18

作者：

Chen, J ^{[1
]}

Prestwich, GD ^{[1
]}

机构：

[1] Univ Utah, Dept Med Chem, Salt Lake City, UT 84112 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1998年 / 63卷 / 03期

关键词：

D O I：

10.1021/jo972046p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[No abstract available]

引用

页码：430 / 431

页数：2

共 28 条

[21] CHEMISTRY OF INOSITOL LIPID-MEDIATED CELLULAR SIGNALING [J].

POTTER, BVL ;

LAMPE, D .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1995, 34 (18) :1933-1972

[22] Touching all the bases: Synthesis of inositol polyphosphate and phosphoinositide affinity probes from glucose [J].

Prestwich, GD .

ACCOUNTS OF CHEMICAL RESEARCH, 1996, 29 (10) :503-513

[23]

REBECCHI MJ, 1993, J BIOL CHEM, V268, P1735

[24] Regulation of phosphoinositide-specific phospholipase C isozymes [J].

Rhee, SG ;

Bae, YS .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (24) :15045-15048

[25] Phosphoinositide binding specificity among phospholipase C isozymes as determined by photo-cross-linking to novel substrate and product analogs [J].

Tall, E ;

Dorman, G ;

Garcia, P ;

Runnels, L ;

Shah, S ;

Chen, J ;

Profit, A ;

Gu, QM ;

Chaudhary, A ;

Prestwich, GD ;

Rebecchi, MJ .

BIOCHEMISTRY, 1997, 36 (23) :7239-7248

[26] SYNTHESIS OF ISOSTERIC AND ISOPOLAR PHOSPHONATE SUBSTRATE-ANALOGS DESIGNED AS INHIBITORS FOR PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE-C FROM BACILLUS-CEREUS [J].

VINOD, TK ;

GRIFFITH, OH ;

KEANA, JFW .

TETRAHEDRON LETTERS, 1994, 35 (39) :7193-7196

[27] Structural views of phosphoinositide-specific phospholipase C: Signalling the way ahead [J].

Williams, RL ;

Katan, M .

STRUCTURE, 1996, 4 (12) :1387-1394

[28] Stereocontrolled syntheses of water-soluble inhibitors of phosphatidylinositol-specific phospholipase C: Inhibition enhanced by an interface [J].

Wu, YQ ;

Zhou, C ;

Roberts, MF .

BIOCHEMISTRY, 1997, 36 (02) :356-363

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