Activities of the glycylcycline tigecycline (GAR-936) against 1,924 recent European clinical bacterial isolates

被引:113
作者
Milatovic, D [1 ]
Schmitz, FJ [1 ]
Verhoef, J [1 ]
Fluit, AC [1 ]
机构
[1] Univ Utrecht Hosp, Eijkman Winkler Inst Med Microbiol, NL-3584 CX Utrecht, Netherlands
关键词
D O I
10.1128/AAC.47.1.400-404.2003
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The in vitro activities of tigecycline against 1,924 clinical isolates were examined. The new glycylcycline exhibited excellent activity against all gram-positive cocci (MICs at which 90% of the isolates tested were inhibited [MIC(90)s], less than or equal to1 mug/ml). In addition, it was also very potent against most members of the Enterobacteriaceae, with most MIC(90)s being less than or equal to2 mug/ml. Among the nonfermenters, Acinetobacter spp. and Stenotrophomonas maltophilia are included in the in vitro spectrum of tigecycline activity.
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页码:400 / 404
页数:5
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