SELEX and the evolution of genomes

被引：21

作者：

Gold, L

Singer, B

He, YY

Brody, E

机构：

[1] NeXstar Pharmaceut, Boulder, CO 80301 USA

[2] Univ Colorado, Dept Mol Cellular & Dev Biol, Boulder, CO 80309 USA

[3] CNRS, Ctr Mol Genet, F-91190 Gif Sur Yvette, France

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1997年 / 7卷 / 06期

关键词：

D O I：

10.1016/S0959-437X(97)80050-0

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The interrupted genome structures of complex multicellular organisms have most likely changed the evolution of the regulation of metabolism and development. Wasted intron sequences make regulation of gene expression in (for example) mammals appear to be unnecessarily complicated. The recent discoveries that globular RNA molecules are very much like the antigen-combining sites of antibodies suggest that intronic RNA may be used to help solve the problems raised by this complexity. (C) Current Biology Ltd ISSN 0959-437X.

引用

收藏

页码：848 / 851

页数：4

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