Intracoronary Optical Coherence Tomography: A Comprehensive Review Clinical and Research Applications

被引:533
作者
Bezerra, Hiram G. [1 ]
Costa, Marco A. [1 ]
Guagliumi, Giulio [3 ]
Rollins, Andrew M. [2 ]
Simon, Daniel I. [1 ]
机构
[1] Case Western Reserve Univ, Sch Med, Univ Hosp,Case Med Ctr, Harrington McLaughlin Heart & Vasc Inst, Cleveland, OH 44106 USA
[2] Case Western Reserve Univ, Sch Med, Dept Biomed Engn, Cleveland, OH 44106 USA
[3] Osped Riuniti Bergamo, Cardiovasc Dept, I-24100 Bergamo, Italy
关键词
optical coherence tomography; coronary; stent; atherosclerosis; INTRAVASCULAR ULTRASOUND GUIDANCE; ACUTE MYOCARDIAL-INFARCTION; ELUTING STENT IMPLANTATION; CULPRIT CORONARY-ARTERY; ANGIOGRAPHIC GUIDANCE; FOLLOW-UP; RESOLUTION; PLAQUE; THROMBOSIS; MALAPPOSITION;
D O I
10.1016/j.jcin.2009.06.019
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cardiovascular optical coherence tomography (OCT) is a catheter-based invasive imaging system. Using light rather than ultrasound, OCT produces high-resolution in vivo images of coronary arteries and deployed stents. This comprehensive review will assist practicing interventional cardiologists in understanding the technical aspects of OCT based upon the physics of light and will also highlight the emerging research and clinical applications of OCT. Semi-automated imaging analyses of OCT systems permit accurate measurements of luminal architecture and provide insights regarding stent apposition, overlap, neointimal thickening, and, in the case of bioabsorbable stents, information regarding the time course of stent dissolution. The advantages and limitations of this new imaging modality will be discussed with emphasis on key physical and technical aspects of intracoronary image acquisition, current applications, definitions, pitfalls, and future directions. (J Am Coll Cardiol Intv 2009;2:1035-46)
引用
收藏
页码:1035 / 1046
页数:12
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