Classical cadherin adhesion molecules are fundamental determinants of tissue organization in both health and disease. Recent advances in understanding the molecular and cellular basis of cadherin function have revealed that these adhesion molecules serve as molecular couplers, linking cell surface adhesion and recognition to both the actin cytoskeleton and cell signalling pathways. We will review some of these developments. to provide an overview of progress in this rapidly-developing area of cell and developmental biology.
机构:
Mem Sloan Kettering Canc Ctr, Cellular Biochem & Biophys Program, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Cellular Biochem & Biophys Program, New York, NY 10021 USA
Niessen, CM
Gumbiner, BM
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机构:
Mem Sloan Kettering Canc Ctr, Cellular Biochem & Biophys Program, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Cellular Biochem & Biophys Program, New York, NY 10021 USA
机构:
CRLC Val Aurelle Paul Larmarque, Equipe Genome & Canc, UMR 5535, CNRS, F-34298 Montpellier 5, FranceCRLC Val Aurelle Paul Larmarque, Equipe Genome & Canc, UMR 5535, CNRS, F-34298 Montpellier 5, France
机构:
Mem Sloan Kettering Canc Ctr, Cellular Biochem & Biophys Program, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Cellular Biochem & Biophys Program, New York, NY 10021 USA
Niessen, CM
Gumbiner, BM
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Cellular Biochem & Biophys Program, New York, NY 10021 USAMem Sloan Kettering Canc Ctr, Cellular Biochem & Biophys Program, New York, NY 10021 USA
机构:
CRLC Val Aurelle Paul Larmarque, Equipe Genome & Canc, UMR 5535, CNRS, F-34298 Montpellier 5, FranceCRLC Val Aurelle Paul Larmarque, Equipe Genome & Canc, UMR 5535, CNRS, F-34298 Montpellier 5, France