Comprehensive survey of combinatorial library synthesis: 1999

被引：194

作者：

Dolle, RE ^{[1
]}

机构：

[1] Pharmacopeia Inc, Dept Chem, Princeton, NJ 08543 USA

来源：

JOURNAL OF COMBINATORIAL CHEMISTRY | 2000年 / 2卷 / 05期

关键词：

D O I：

10.1021/cc000055x

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

[No abstract available]

引用

页码：383 / 433

页数：51

共 300 条

[1] Combinatorial library of serine and cysteine protease inhibitors that interact with both the S and S′ binding sites [J].

Abate, P ;

Conroy, JL ;

Seto, CT .

JOURNAL OF MEDICINAL CHEMISTRY, 1999, 42 (19) :4001-4009

[2] Solution-phase and solid-phase synthesis of novel transition state inhibitors of coagulation enzymes incorporating a piperidinyl moiety [J].

Adang, AEP ;

Peters, CAM ;

Gerritsma, S ;

de Zwart, E ;

Veeneman, G .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1999, 9 (09) :1227-1232

[3] Studies towards the identification of potent, selective and bioavailable thrombin inhibitors [J].

Ambler, J ;

Baker, E ;

Bentley, D ;

Brown, L ;

Butler, K ;

Butler, P ;

Farr, D ;

Dunnet, K ;

Le Grand, D ;

Hayler, J ;

Janus, D ;

Jones, D ;

Menear, K ;

Mercer, M ;

Smith, G ;

Talbot, M ;

Tweed, M .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1999, 9 (05) :737-742

[4] The synthesis and evaluation of a solution-phase indexed combinatorial library of non-natural polyenes for multidrug resistance reversal [J].

Andrus, MB ;

Turner, TM ;

Asgari, D ;

Li, WK .

JOURNAL OF ORGANIC CHEMISTRY, 1999, 64 (09) :2978-2979

[5] Demonstration of the strength of focused combinatorial libraries in SAR optimisation of growth hormone secretagogues [J].

Ankersen, M ;

Hansen, BS ;

Hansen, TK ;

Lau, J ;

Peschke, B ;

Madsen, K ;

Johansen, NL .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1999, 34 (10) :783-790

[6] Development of a reductive alkylation method using p-benzyloxybenzylamine (BOBA) resin for the synthesis of N-alkylated amides [J].

Aoki, Y ;

Kobayashi, S .

JOURNAL OF COMBINATORIAL CHEMISTRY, 1999, 1 (05) :371-372

[7] Identification of novel antitumor agents from mixture-based synthetic combinatorial libraries using cell-based assays [J].

Appel, JR ;

Johnson, J ;

Narayanan, VL ;

Houghten, RA .

MOLECULAR DIVERSITY, 1998, 4 (02) :91-102

[8] Potent and orally bioavailable noncysteine-containing inhibitors of protein farnesyltransferase [J].

Augeri, DJ ;

Janowick, D ;

Kalvin, D ;

Sullivan, G ;

Larsen, J ;

Dickman, D ;

Ding, H ;

Cohen, J ;

Lee, J ;

Warner, R ;

Kovar, P ;

Cherian, S ;

Saeed, B ;

Zhang, HC ;

Tahir, S ;

Ng, SC ;

Sham, H ;

Rosenberg, SH .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1999, 9 (08) :1069-1074

[9] Solid-phase synthesis of novel inhibitors of farnesyl transferase [J].

Barber, AM ;

Hardcastle, IR ;

Rowlands, MG ;

Nutley, BP ;

Marriott, JH ;

Jarman, M .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1999, 9 (04) :623-626

[10] Solid-phase synthesis of hydroxamic acid based TNF-α convertase inhibitors [J].

Barlaam, B ;

Koza, P ;

Berriot, J .

TETRAHEDRON, 1999, 55 (23) :7221-7232

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