The mRNA level of the circadian regulated Gonyaulax luciferase remains constant over the cycle

被引:45
作者
Mittag, M [1 ]
Li, LM [1 ]
Hastings, JW [1 ]
机构
[1] Harvard Univ, Dept Mol & Cellular Biol, Cambridge, MA 02138 USA
基金
美国国家科学基金会;
关键词
D O I
10.3109/07420529808998673
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The expression of luciferin-binding protein (LBP) and luciferase (LCF), two proteins that are involved in bioluminescence in Gonyaulax polyedra, is controlled by a cellular circadian clock. In the case of LBP, its temporal expression is reported to be regulated at the translational level, involving both 5' and 3' untranslated regions (UTRs) of lbp mRNA. Here, we show that the amounts of lcf mRNA are constant throughout the day-night cycle, indicating that the circadian expression of LCF is also regulated at the translational level.
引用
收藏
页码:93 / 98
页数:6
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