High-resolution genotyping of Chlamydia trachomatis from recurrent urogenital infections

被引：27

作者：

Pedersen, LN

Kjær, HO

Moller, JK

Orntoft, TF

Ostergaard, L

机构：

[1] Aarhus Kommune Hosp, Dept Clin Microbiol, DK-8000 Aarhus, Denmark

[2] Marselisborg Hosp, Dept Infect Dis, DK-8000 Aarhus, Denmark

[3] Horsens Cty Hosp, Dept Internal Med, DK-8700 Horsens, Denmark

[4] Skejby Hosp, Dept Clin Biochem, DK-8200 Aarhus N, Denmark

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2000年 / 38卷 / 08期

关键词：

D O I：

10.1128/JCM.38.8.3068-3071.2000

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A method for Chlamydia trachomatis restriction fragment length polymorphism (RFLP) analysis and complete sequencing of omp1 was developed for use on samples collected at home, and results were compared. Genotyping by sequencing was superior to RFLP analysis. The omp1 gene in 31 clinical strains harbored few mutations compared to the same gene in ATCC reference strains. Follow-up samples obtained during a 24-week period from 31 patients showed recurrence with the same genotype in five cases and a new genotype in one case.

引用

页码：3068 / 3071

页数：4

共 16 条

[11] Efficacy of home sampling for screening of Chlamydia trachomatis:: randomised study [J].