The Mammalian Phenotype Ontology as a tool for annotating, analyzing and comparing phenotypic information

被引:270
作者
Smith, CL
Goldsmith, CAW
Eppig, JT
机构
[1] Jackson Lab, Bar Harbor, ME 04609 USA
[2] Massachusetts Coll Pharm & Hlth Sci, Sch Pharm Manchester, Manchester, NH 03101 USA
关键词
D O I
10.1186/gb-2004-6-1-r7
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The Mammalian Phenotype ( MP) Ontology enables robust annotation of mammalian phenotypes in the context of mutations, quantitative trait loci and strains that are used as models of human biology and disease. The MP Ontology supports different levels and richness of phenotypic knowledge and flexible annotations to individual genotypes. It continues to develop dynamically via collaborative input from research groups, mutagenesis consortia, and biological domain experts. The MP Ontology is currently used by the Mouse Genome Database and Rat Genome Database to represent phenotypic data.
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页数:9
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