Lipase-mediated chiral resolution of racemates in organic solvents

被引：251

作者：

Ghanem, A

Aboul-Enein, HY

机构：

[1] Univ Geneva, Dept Organ Chem, CH-1211 Geneva 4, Switzerland

[2] King Faisal Specialist Hosp & Res Ctr, Biol & Med Res Dept MBC 03 65, Pharmaceut Anal Lab, Riyadh 11211, Saudi Arabia

来源：

TETRAHEDRON-ASYMMETRY | 2004年 / 15卷 / 21期

关键词：

D O I：

10.1016/j.tetasy.2004.09.019

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Lipase-catalyzed kinetic resolution of racemates is considered to be one of the most fascinating topics in asymmetric catalysis. This review focuses on some of the recent developments in this rapidly growing field demonstrating the versatility of the method in the resolution of racemates. The literature search is dated back to the last five years and covers some comprehensive examples. The main emphasis is on the use of lipases in organic solvents. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：3331 / 3351

页数：21

共 116 条

[1] Use of lipase-catalyzed kinetic resolution for the enantioselective approach toward sesquiterpenes containing quaternary centers: the cuparane family [J].