Chiral ligand-controlled asymmetric conjugate addition of lithium amides to enoates

被引：100

作者：

Doi, H ^{[1
]}

Sakai, T ^{[1
]}

Iguchi, M ^{[1
]}

Yamada, K ^{[1
]}

Tomioka, K ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Pharmaceut Sci, Sakyo Ku, Kyoto 6068501, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 10期

关键词：

D O I：

10.1021/ja029633z

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The external chiral ligand-controlled asymmetric conjugate addition reaction of lithium amides with α,β-unsaturated esters provided β-amino esters in high yields and high enantioselectivities. Copyright © 2003 American Chemical Society.

引用

页码：2886 / 2887

页数：2

共 57 条

[21] ASYMMETRIC MICHAEL REACTIONS OF 3,5-DIHYDRO-4H-DINAPHTH[2,1-C-1',2'-E]AZEPINE WITH METHYL CROTONATE
HAWKINS, JM
FU, GC
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1986, 51 (14) : 2820 - 2822
[22] THE CHEMISTRY OF ACTIVATED BLEOMYCIN
HECHT, SM
[J]. ACCOUNTS OF CHEMICAL RESEARCH, 1986, 19 (12) : 383 - 391
[23] JAURISTI E, 1997, ENANTIOSELECTIVE SYN
[24] Highly diastereoselective and enantioselective carbon-carbon bond formations in conjugate additions of lithiated N-boc allylamines to nitroalkenes:: Enantioselective synthesis of 3,4-and 3,4,5-substituted piperidines including (-)-paroxetine
Johnson, TA
Curtis, MD
Beak, P
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (05) : 1004 - 1005
[25] CATALYTIC ASYMMETRIC CONJUGATE ADDITION OF GRIGNARD-REAGENTS MEDIATED BY COPPER(I)-CHIRAL BIDENTATE PHOSPHINE COMPLEX
KANAI, M
TOMIOKA, K
[J]. TETRAHEDRON LETTERS, 1995, 36 (24) : 4275 - 4278
[26] Krause N, 2001, SYNTHESIS-STUTTGART, P171
[27] Hemilabile amidomonophosphine ligand-rhodium(I) complex-catalyzed asymmetric 1,4-addition of arylboronic acids to cycloalkenones
Kuriyama, M
Nagai, K
Yamada, K
Miwa, Y
Taga, T
Tomioka, K
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (30) : 8932 - 8939
[28] Enantioselective synthesis of α,α-disubstituted amines from nitroalkenes
Leroux, ML
Le Gall, T
Mioskowski, C
[J]. TETRAHEDRON-ASYMMETRY, 2001, 12 (13) : 1817 - 1823
[29] Recent advances in the stereoselective synthesis of β-amino acids
Liu, M
Sibi, MP
[J]. TETRAHEDRON, 2002, 58 (40) : 7991 - 8035
[30] LUKACS G, 1990, RECENT PROGR CHEM SY

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