Current status of TB vaccines

被引：67

作者：

Gupta, Umesh Datta

Katoch, Vishwa Mohan

McMurray, David N.

机构：

[1] Natl JALMA Inst Leprosy & Other Mycobacterial Dis, ICMR, Agra 282001, Uttar Pradesh, India

[2] Texas A&M Univ, Syst Hlth Sci Ctr, Dept Microbial & Mol Pathogenesis, College Stn, TX 77843 USA

来源：

VACCINE | 2007年 / 25卷 / 19期

关键词：

DNA vaccines; attenuated vaccines; sub-unit vaccines;

D O I：

10.1016/j.vaccine.2007.01.112

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

During last 10 years, there has been extensive work for the development of potential tuberculosis vaccine candidates using the mice and guinea pig models. Though till date several promising candidates have been identified and at least eight vaccines have entered clinical evaluation. These recent advances in the clinical testing of new TB vaccines are very exciting and promising. However, there is a need to continue the search for additional vaccine candidates or vaccination strategies. Published by Elsevier Ltd.

引用

收藏

页码：3742 / 3751

页数：10

相关论文

共 123 条

[1] Immunogenicity and protection induced by Mycobacterium tuberculosis mce-2 and mce-3 mutants in a Balb/c mouse model of progressive pulmonary tuberculosis [J].

Aguilar, LD ;

Infante, E ;

Bianco, MV ;

Cataldi, A ;

Bigi, F ;

Pando, RH .

VACCINE, 2006, 24 (13) :2333-2342

[2] Mice fed lipid-encapsulated Mycobacterium bovis BCG are protected against aerosol challenge with Mycobacterium tuberculosis [J].

Aldwell, FE ;

Brandt, L ;

Fitzpatrick, C ;

Orme, IM .

INFECTION AND IMMUNITY, 2005, 73 (03) :1903-1905

[3]

ANDERSEN P, 1995, J IMMUNOL, V154, P3359

[4]

ARREOLA MC, 2005, TUBERCULOSIS, V85, P115

[5] Evaluation of new vaccines in the mouse and guinea pig model of tuberculosis [J].

Baldwin, SL ;

D'Souza, C ;

Roberts, AD ;

Kelly, BP ;

Frank, AA ;

Lui, MA ;

Ulmer, JB ;

Huygen, K ;

McMurray, DM ;

Orme, IM .

INFECTION AND IMMUNITY, 1998, 66 (06) :2951-2959

[6] Comparative genomics of BCG vaccines [J].

Behr, MA .

TUBERCULOSIS, 2001, 81 (1-2) :165-168

[7]

Bishai DM, 2001, INT J TUBERC LUNG D, V5, P984

[8]

Bloom Barry R., 1994, P531

[9] The protective effect of the Mycobacterium bovis BCG vaccine is increased by coadministration with the Mycobacterium tuberculosis 72-kilodalton fusion polyprotein Mtb72F in M-tuberculosis-infected guinea pigs [J].

Brandt, L ;

Skeiky, YAW ;

Alderson, MR ;

Lobet, Y ;

Dalemans, W ;

Turner, OC ;

Basaraba, RJ ;

Izzo, AA ;

Lasco, TM ;

Chapman, PL ;

Reed, SG ;

Orme, IM .

INFECTION AND IMMUNITY, 2004, 72 (11) :6622-6632

[10] Failure of the Mycobacterium bovis BCG vaccine:: Some species of environmental mycobacteria block multiplication of BCG and induction of protective immunity to tuberculosis [J].

Brandt, L ;

Cunha, JF ;

Olsen, AW ;

Chilima, B ;

Hirsch, P ;

Appelberg, R ;

Andersen, P .

INFECTION AND IMMUNITY, 2002, 70 (02) :672-678

← 1 2 3 4 5 6 7 8 9 10 →