Current status of TB vaccines

被引:67
作者
Gupta, Umesh Datta
Katoch, Vishwa Mohan
McMurray, David N.
机构
[1] Natl JALMA Inst Leprosy & Other Mycobacterial Dis, ICMR, Agra 282001, Uttar Pradesh, India
[2] Texas A&M Univ, Syst Hlth Sci Ctr, Dept Microbial & Mol Pathogenesis, College Stn, TX 77843 USA
关键词
DNA vaccines; attenuated vaccines; sub-unit vaccines;
D O I
10.1016/j.vaccine.2007.01.112
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
During last 10 years, there has been extensive work for the development of potential tuberculosis vaccine candidates using the mice and guinea pig models. Though till date several promising candidates have been identified and at least eight vaccines have entered clinical evaluation. These recent advances in the clinical testing of new TB vaccines are very exciting and promising. However, there is a need to continue the search for additional vaccine candidates or vaccination strategies. Published by Elsevier Ltd.
引用
收藏
页码:3742 / 3751
页数:10
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