Cytogenetic analysis of early nonviable pregnancies after assisted reproduction treatment

被引:70
作者
Carmen Martinez, M. [1 ]
Mendez, Carmen [1 ]
Ferro, Jaime [2 ]
Nicolas, Maria [1 ]
Serra, Vicente [2 ]
Landeras, Jose [1 ]
机构
[1] IVI Murcia, Murcia 30007, Spain
[2] Inst Valenciano Infertilidad, Valencia, Spain
关键词
IN-VITRO FERTILIZATION; INTRACYTOPLASMIC SPERM INJECTION; PREIMPLANTATION GENETIC DIAGNOSIS; SPONTANEOUS-ABORTIONS; CHROMOSOME-ABNORMALITIES; ICSI; ANEUPLOIDY; EMBRYOS; IVF; AGE;
D O I
10.1016/j.fertnstert.2009.07.989
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
In our series, a very high prevalence of chromosomal abnormalities was observed in spontaneous miscarriages, irrespective of how pregnancy was achieved, by assisted reproductive technology (ART) or natural conception. This high prevalence was equally represented in both groups, with no statistical difference in type of chromosomal abnormalities or in total frequency; however, the incidence of monosomy X is increased and the polyploidies are decreased in abortus after intracytoplasmic sperm injection (ICSI) when it is compared with miscarriages after spontaneous gestations. (Fertil Steril(R) 20 10;93:289-92. (C)2010 by American Society for Reproductive Medicine.)
引用
收藏
页码:289 / 292
页数:4
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