Enantioselective synthesis of 5-substituted pipecolic acids using an intramolecular allylsilane-iminium ion cyclization

被引：18

作者：

Cellier, M

Gelas-Mialhe, Y ^{[1
]}

Husson, HP

Perrin, B

Remuson, R

机构：

[1] Univ Clermont Ferrand 2, UMR 6504, Lab Chim Subst Nat, F-63177 Clermont Ferrand, France

[2] Univ Paris 05, CNRS, UMR 8638, Chim Therapeut Lab,Fac Sci Pharmaceut & Biol, F-75270 Paris 06, France

来源：

TETRAHEDRON-ASYMMETRY | 2000年 / 11卷 / 19期

关键词：

D O I：

10.1016/S0957-4166(00)00361-X

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The application of the intramolecular allylsilane-iminium ion cyclization reaction for the enantioselective synthesis of piperidine derivatives is described. The synthetic potential of this methodology is demonstrated by the enantioselective synthesis of 5-substituted pipecolic acids. (C) 2000 Elsevier Science Ltd. All rights reserved.

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页码：3913 / 3919

页数：7

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