IVIAT: a novel method to identify microbial genes expressed specifically during human infections

被引：80

作者：

Handfield, M

Brady, LJ

Progulske-Fox, A

Hillman, JD

机构：

[1] Univ Florida, Coll Dent, Ctr Mol Microbiol, Gainesville, FL 32610 USA

[2] Univ Florida, Coll Dent, Dept Oral Biol, Gainesville, FL 32610 USA

来源：

TRENDS IN MICROBIOLOGY | 2000年 / 8卷 / 07期

关键词：

D O I：

10.1016/S0966-842X(00)01775-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In vivo induced antigen technology (IVIAT) Is a novel technology that can quickly and easily identify in vivo induced genes in human infections, without the use of animal models. This technology is expected to facilitate the discovery of new targets for vaccines, antimicrobials and diagnostic strategies in a wide range of microbial pathogens.

引用

页码：336 / 339

页数：4

共 7 条

[1] In vivo genetic analysis of bacterial virulence [J].