Synthesis and structure-activity relationships of novel THF 1β-metylcarbapenems -: II

被引：3

作者：

Lin, YI ^{[1
]}

Bitha, P ^{[1
]}

Sakya, SM ^{[1
]}

Lang, SA ^{[1
]}

Yang, YJ ^{[1
]}

Weiss, WJ ^{[1
]}

Petersen, PJ ^{[1
]}

Bush, K ^{[1
]}

Testa, RT ^{[1
]}

机构：

[1] Wyeth Ayerst Res, Infect Dis Res Sect, Pearl River, NY 10965 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1997年 / 7卷 / 23期

关键词：

D O I：

10.1016/S0960-894X(97)10143-3

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two series of active aminomethyl-THF 1 beta-methylcarbapenem derivatives were synthesized. In general, they were all slightly less active than their parent compounds and failed to demonstrate enhanced activity against P. aeruginosa. (C) 1997 Elsevier Science Ltd.

引用

页码：3063 / 3068

页数：6

共 16 条

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