Solid phase synthesis of 2,4-disubstituted pyridine and tetrahydropyridine derivatives: Resin activation capture approach REACAP technology

被引：22

作者：

Chen, CX ^{[1
]}

Munoz, B ^{[1
]}

机构：

[1] SIBIA Neurosci Inc, La Jolla, CA 92037 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 21期

关键词：

D O I：

10.1016/S0040-4039(98)00533-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The resin-bound dihydropyridone scaffold generated using the Resin Activation/Capture Approach (REACAP) Technology was further elaborated to afford 2,4-disubstituted pyridine and tetrahydropyridine derivatives. This process can be envisaged as the functionalization of pyridine analogues on solid support by a traceless linker approach. (C) 1998 Elsevier Science Ltd. All rights reserved.

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页码：3401 / 3404

页数：4

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