The direct synthesis of novel enantiomerically pure α-amino acids in protected form via Suzuki cross-coupling

被引：36

作者：

Collier, PN

Campbell, AD

Patel, I

Taylor, RJK ^{[1
]}

机构：

[1] Univ York, Dept Chem, York Y010 5DD, N Yorkshire, England

[2] Astrazeneca, Bristol BS10 7ZE, Avon, England

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 36期

关键词：

D O I：

10.1016/S0040-4039(00)01174-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Protected allylglycine has been hydroborated and the intermediate organoborane employed in Suzuki coupling reactions with a number of olefinic, aromatic and heteroaromatic bromides and iodides to produce a range of novel a-amino acids in good, unoptimised yields. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：7115 / 7119

页数：5

共 24 条

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