Characterization of a small mobilizable transposon, MTnSag1, in Streptococcus agalactiae

被引:23
作者
Achard, Adeline
Leclercq, Roland
机构
[1] Univ Caen, Microbiol Serv, F-14033 Caen, France
[2] Univ Caen, EA Interact Hote & Microorganismes Epitheliums, CHU Cote Nacre, F-14033 Caen, France
关键词
D O I
10.1128/JB.00213-07
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The transposon MTnSag1 from Streptococcus agalactiae carried an IS1-like transposase gene and the lnu(C) gene, which encoded a lincosamide nucleotidyltransferase. MTnSag1 could be mobilized by the conjugative transposon Tn916. An intermediate circular form of MTnSag1 and a putative origin of transfer at the 3' end of the Inu(C) gene were characterized.
引用
收藏
页码:4328 / 4331
页数:4
相关论文
共 17 条
[1]   New lnu(C) gene conferring resistance to lincomycin by nucleotidylation in Streptococcus agalactiae UCN36 [J].
Achard, A ;
Villers, C ;
Pichereau, V ;
Leclercq, R .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (07) :2716-2719
[2]   The clostridial mobilisable transposons [J].
Adams, V ;
Lyras, D ;
Farrow, KA ;
Rood, JI .
CELLULAR AND MOLECULAR LIFE SCIENCES, 2002, 59 (12) :2033-2043
[3]   Functional domains of the IS1 transposase:: analysis in vivo and in vitro [J].
Bao, TH ;
Turlan, C ;
Chandler, M .
MOLECULAR MICROBIOLOGY, 2004, 53 (05) :1529-1543
[4]   Circularization of Tn916 is required for expression of the transposon-encoded transfer functions:: characterization of long tetracycline-inducible transcripts reading through the attachment site [J].
Celli, J ;
Trieu-Cuot, P .
MOLECULAR MICROBIOLOGY, 1998, 28 (01) :103-117
[5]   Group B streptococcal disease in nonpregnant adults [J].
Farley, MM .
CLINICAL INFECTIOUS DISEASES, 2001, 33 (04) :556-561
[6]   Genomic analysis of the erythromycin resistance element Tn5398 from Clostridium difficile [J].
Farrow, KA ;
Lyras, D ;
Rood, JI .
MICROBIOLOGY-SGM, 2001, 147 :2717-2728
[7]   Specific binding of integrase to the origin of transfer (oriT) of the conjugative transposon Tn916 [J].
Hinerfeld, D ;
Churchward, G .
JOURNAL OF BACTERIOLOGY, 2001, 183 (09) :2947-2951
[8]   A FUNCTIONAL ORIGIN OF TRANSFER (ORIT) ON THE CONJUGATIVE TRANSPOSON TN916 [J].
JAWORSKI, DD ;
CLEWELL, DB .
JOURNAL OF BACTERIOLOGY, 1995, 177 (22) :6644-6651
[9]   Insertion sequences [J].
Mahillon, J ;
Chandler, M .
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 1998, 62 (03) :725-+
[10]   Genetic basis of antibiotic resistance in Streptococcus agalactiae strains isolated in a French hospital [J].
Poyart, C ;
Jardy, L ;
Quesne, G ;
Berche, P ;
Trieu-Cuot, P .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (02) :794-797