Separation of enantiomers with charged chiral selectors in CE

被引：108

作者：

Chankvetadze, Bezhan ^{[1
]}

机构：

[1] Tbilisi State Univ, Sch Exact & Nat Sci, Dept Phys & Analyt Chem, GE-0179 Tbilisi, Georgia

来源：

ELECTROPHORESIS | 2009年 / 30卷

关键词：

Charged chiral selectors; Enantioseparations; IONIZATION-MASS-SPECTROMETRY; NONAQUEOUS CAPILLARY-ELECTROPHORESIS; SINGLE-ISOMER; BETA-CYCLODEXTRIN; ELECTROKINETIC CHROMATOGRAPHY; BACKGROUND ELECTROLYTES; RESOLVING AGENTS; MIGRATION ORDER; DERIVATIZED CYCLODEXTRINS; NEUTRAL CYCLODEXTRINS;

D O I：

10.1002/elps.200900102

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

In this short overview the major developments in separation of enantiomers with charged chiral selectors are summarized in CE. The advantages of charged chiral selectors in comparison with their uncharged analogues are emphasized from the viewpoints of higher flexibility, higher and alternative separation selectivity, as well as alternative chiral recognition mechanism.

引用

页码：S211 / S221

页数：11

共 69 条

[31] Comparative capillary electrophoretic and nuclear magnetic resonance studies of the chiral recognition of racemic metomidate with cyclodextrin hosts [J].

Endresz, G ;

Chankvetadze, B ;

Bergenthal, D ;

Blaschke, G .

JOURNAL OF CHROMATOGRAPHY A, 1996, 732 (01) :133-142

[32] Chiral capillary electrophoresis electrospray mass spectrometry coupling using vancomycin as chiral selector [J].

Fanali, S ;

Desiderio, C ;

Schulte, G ;

Heitmeier, S ;

Strickmann, D ;

Chankvetadze, B ;

Blaschke, G .

JOURNAL OF CHROMATOGRAPHY A, 1998, 800 (01) :69-76

[33]

Fanali S, 1996, J HIGH RES CHROMATOG, V19, P322

[34] Use of electrostatic interaction for chiral recognition. Enantioselective complexation of anionic binaphthyls with protonated amino-beta-cyclodextrin [J].

Kano, K ;

Kitae, T ;

Takashima, H .

JOURNAL OF INCLUSION PHENOMENA AND MOLECULAR RECOGNITION IN CHEMISTRY, 1996, 25 (1-3) :243-248

[35] About the role of enantioselective selector-selectand interactions and the mobilities of diastereomeric associates in enantiomer separations using CE [J].

Lomsadze, Ketevan ;

Martinez-Giron, Ana B. ;

Castro-Puyana, Maria ;

Chankvetadze, Lali ;

Crego, Antonio L. ;

Salgado, Antonio ;

Luisa Marina, Maria ;

Chankvetadze, Bezhan .

ELECTROPHORESIS, 2009, 30 (16) :2803-2811

[36] Nonaqueous capillary electrophoresis method for the enantiomeric purity determination of S-timolol using heptakis(2,3-di-O-methyl-6-O-sulfo)-β-cyclodextrin:: Validation using the accuracy profile strategy and estimation of uncertainty [J].

Marini, Roland Djang'eing'a ;

Servais, Anne-Catherine ;

Rozet, Eric ;

Chiap, Patrice ;

Boulanger, Bruno ;

Rudaz, Serge ;

Crommen, Jacques ;

Hubert, Philippe ;

Fillet, Marianne .

JOURNAL OF CHROMATOGRAPHY A, 2006, 1120 (1-2) :102-111

[37] DUAL CHIRAL RECOGNITION SYSTEM INVOLVING CYCLODEXTRIN DERIVATIVES IN CAPILLARY ELECTROPHORESIS [J].

MAYER, S ;

SCHLEIMER, M ;

SCHURIG, V .

JOURNAL OF MICROCOLUMN SEPARATIONS, 1994, 6 (01) :43-48

[38] ENANTIOMER SEPARATION USING MOBILE AND IMMOBILE CYCLODEXTRIN DERIVATIVES WITH ELECTROMIGRATION [J].

MAYER, S ;

SCHURIG, V .

ELECTROPHORESIS, 1994, 15 (06) :835-841

[39] Synthesis and analytical characterization of the sodium salt of heptakis(2-O-methyl-3,6-di-O-sulfo)cyclomalto-heptaose, a chiral resolving agent candidate for capillary electrophoresis [J].

Maynard, DK ;

Vigh, G .

CARBOHYDRATE RESEARCH, 2000, 328 (03) :277-285

[40] A RESOLUTION EQUATION FOR ELECTROKINETIC CHROMATOGRAPHY BASED ON ELECTROPHORETIC MOBILITIES [J].

MAZZEO, JR ;

SWARTZ, ME ;

GROVER, ER .

ANALYTICAL CHEMISTRY, 1995, 67 (17) :2966-2973

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